Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.060 Biomarker disease BEFREE In summary, Lrig1 is a haploinsufficient suppressor of PDGFB-driven glioma, possibly in part via negative regulation of MET-driven cell migration and invasion. 29391393 2018
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.060 Biomarker disease BEFREE The phenotype of Lrig2E12-/- mice showed that Lrig2 was a promoter of PDGFB-induced glioma, and Lrig2 appeared to have important molecular and developmental functions that were distinct from those of Lrig1 and Lrig3. 24023893 2013
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.060 AlteredExpression disease BEFREE Expression of PDGFB is thought to be important in the pathogenesis of glioma and several animal models of cerebral glioma based on PDGF expression have been described. 18922925 2008
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.060 Biomarker disease LHGDN High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. 17292826 2007
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.060 Biomarker disease LHGDN Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells. 14997209 2004
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
0.060 AlteredExpression disease BEFREE Activation of glioma c-sis gene expression is therefore not the result of a gross rearrangement or amplification of the c-sis gene. 2585029 1989