Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 Biomarker disease BEFREE Synthesis and evaluation of <sup>18</sup>F-hexafluorophosphate as a novel PET probe for imaging of sodium/iodide symporter in a murine C6-glioma tumor model. 29198608 2018
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 Biomarker disease BEFREE 131I therapy mediated by sodium/iodide symporter combined with kringle 5 has a synergistic therapeutic effect on glioma. 26572557 2016
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 GeneticVariation disease BEFREE Various cancer cell lines such as thyroid (TPC-1, FRO, B-CPAP), breast (MDA-MB-231), liver (Hep3B), cervical (HeLa), and glioma (U87MG) were transfected with pcDNA3.1/hNIS or pcDNA3.1/opt-hNIS. 25553100 2015
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 Biomarker disease BEFREE The human glioma cell line U87 was transfected with recombinant lentivirus encoding the hNIS gene under the control of cytomegalovirus promoter (U87-hNIS). 25000403 2014
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 AlteredExpression disease BEFREE In this study, we have demonstrated that MV strains genetically engineered to express the human sodium iodide symporter (NIS) have significant antitumor activity against glioma lines and orthotopic xenografts; this compares favorably with the MV strain expressing the human carcinoembryonic antigen, which is currently in clinical testing. 22185260 2012
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 Biomarker disease BEFREE In the human glioma transfected with NIS, boron concentration was more than 10 fold higher with 100 mg/kg of NaBF(4), compared to tumor not transfected. 20921830 2010
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 Therapeutic disease CTD_human The rat sodium iodide symporter gene permits more effective radioisotope concentration than the human sodium iodide symporter gene in human and rodent cancer cells. 12489024 2003
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
0.370 AlteredExpression disease BEFREE In vitro cytotoxicity of (211)at-astatide and (131)I-iodide to glioma tumor cells expressing the sodium/iodide symporter. 14602867 2003