| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.360 | GeneticVariation | disease | BEFREE | As compared to patients with glomerulonephritis type V (WHO classification), the presumptive IL-10 high producer allele -2849 G was found significantly more often in patients with GN type III/IV (93% vs. 60%; OR 8.7, 95% CI 1.59-47.15). | 24536045 | 2014 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | Carriage of the TGF-beta 1 (codon 10) TT and IL-10 (-1082) GG genotypes may increase susceptibility to ESRD in German patients with type 2 diabetes or glomerulonephritis. | 17173255 | 2007 | ||||
|
0.360 | GeneticVariation | disease | LHGDN | Patients carrying the -592 C allele had a higher risk of diffuse proliferative glomerulonephritis, indicating the genetic influence of the IL-10 gene polymorphism in the renal lesions of LN. | 16396704 | 2006 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | To investigate the effect of IL-10 promoter polymorphisms on the predisposition to development of GN in Korea, IL-10 promoter polymorphisms were assayed by polymerase chain reaction followed by restriction fragment length polymorphism in 108 patients with IgA nephropathy (IgAN), 49 focal segmental glomerulosclerosis (FSGS), and 100 healthy controls. | 16361810 | 2005 | ||||
|
0.360 | GeneticVariation | disease | BEFREE | Association of interleukin-10 gene G-1082A polymorphism with the progression of primary glomerulonephritis. | 15200436 | 2004 | ||||
|
0.360 | Biomarker | disease | CTD_human | Cytokines and T-cell responses in superantigen-related glomerulonephritis following methicillin-resistant Staphylococcus aureus infection. | 10910440 | 2000 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | We looked for the expression of IL-10 and TNF-alpha in 111 renal biopsy specimens with proliferative and nonproliferative forms of GN and in 10 control kidneys, by means of immunocytochemistry, in situ hybridization, or reverse-transcriptase polymerase chain reaction (RT-PCR). | 9669428 | 1998 |