| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | There was no significant difference in IFN‑γ expression between the IgAN and healthy control groups. | 30132546 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | IFN-γ-rs2430561 T allele may be a protective factor for IgAN susceptibility (T vs. A: OR = 0.59, P = 0.04). | 28391282 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Upon the LPS stimulation, the concentration of IL-4, IFN-γ in the supernatant of the IgA nephropathy group was markedly increased compared with the non-IgAN group. | 24732061 | 2014 | ||||
|
0.080 | Biomarker | disease | LHGDN | Increase in B-cell-activation factor (BAFF) and IFN-gamma productions by tonsillar mononuclear cells stimulated with deoxycytidyl-deoxyguanosine oligodeoxynucleotides (CpG-ODN) in patients with IgA nephropathy. | 18249037 | 2008 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Role of interferon-gamma gene polymorphisms in susceptibility to IgA nephropathy: a family-based association study. | 16493441 | 2006 | ||||
|
0.080 | GeneticVariation | disease | LHGDN | We investigated IFN-gamma gene (IFNG) and IL-4 gene (IL4) polymorphisms in 96 patients with biopsy-confirmed IgA nephropathy who were followed-up for more than 3 years in our outpatient clinic and 61 healthy controls by polymerase chain reaction and direct sequencing methods. | 12552499 | 2003 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We investigated IFN-gamma gene (IFNG) and IL-4 gene (IL4) polymorphisms in 96 patients with biopsy-confirmed IgA nephropathy who were followed-up for more than 3 years in our outpatient clinic and 61 healthy controls by polymerase chain reaction and direct sequencing methods. | 12552499 | 2003 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In the present study, we investigated characteristic synthesis of interferon-gamma (IFN-gamma) and expression of IFN-gamma receptor (IFN-gamma R) in the peripheral blood mononuclear cells (PBMC) from patients with IgAN and other chronic proliferative glomerulonephritis (PGN). | 8926288 | 1996 | ||||
|
0.080 | Biomarker | disease | BEFREE | We examined the profile of cytokine mRNA expressed in purified CD4+ cells in patients with IgAN in order to study their pattern of Th1 (releases IL-2 and interferon-gamma (IFN-gamma)) and Th2 (releases IL-4 and IL-5) T cell response. | 7908616 | 1994 |