Gene: RAC1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5879
Gene Symbol: RAC1
RAC1 		0.030 GeneticVariation disease BEFREE Inherited forms of FSGS are caused by Rac1-activating mutations, and Rac1 induces TRPC5 ion channel activity and cytoskeletal remodeling in podocytes. 29217578 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1 		0.030 Biomarker disease BEFREE Activation of Rac1 in podocytes was also seen in kidney biopsies from patients with minimal change disease and idiopathic FSGS by immunofluorescence while sera from the same patients activated Rac1 in cultured human podocytes. 28483380 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1 		0.030 GeneticVariation disease BEFREE Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. 21911940 2011