Gene: AGT ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 Biomarker group BEFREE Angiotensin II-related cardiac fibrosis is one of the key pathological changes of the hypertrophied left ventricle in various heart disease. 30703374 2019
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 AlteredExpression group BEFREE Elevated angiotensin II (Ang II) and sympathetic activity contributes to a high risk of ventricular arrhythmias in heart disease. 28941256 2017
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 GeneticVariation group BEFREE Angiotensin-(1-7) [Ang-(1-7)] exhibits cardiovascular effects opposite those of angiotensin II (Ang II), thus providing protection against heart disease. 28096047 2017
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 Biomarker group BEFREE C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease. 20157054 2010
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 Biomarker group CTD_human Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis. 19373235 2009
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 GeneticVariation group BEFREE The ThrThr genotype of the angiotensinogen (AGT) Met235Thr polymorphism has been associated with elevated AGT levels, hypertension, increased heart disease risk, and improved blood pressure (BP) response to angiotensin-converting enzyme (ACE) inhibitors. 14643574 2003
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 Biomarker group LHGDN Local cardiac renin-angiotensin system: hypertension and cardiac failure. 12431442 2002
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.370 Biomarker group BEFREE The chymase gene is said to be important for the generation of angiotensin II in the heart and therefore is a candidate gene for heart disease. 9794357 1998