×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Therapeutic
phenotype
RGD
Curcumin inhibits cardiac hypertrophy and improves cardiovascular function via enhanced Na
29331788
2018
×
Entrez Id:
1906
Gene Symbol:
EDN1
EDN1
0.510
Biomarker
phenotype
CTD_human
PPARα activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4.
22198280
2012
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
GeneticVariation
phenotype
LHGDN
Gene polymorphisms predisposing to cardiac hypertrophy in patients with cardiac syndrome X.
19051693
2007
×
Entrez Id:
1906
Gene Symbol:
EDN1
EDN1
0.510
GeneticVariation
phenotype
LHGDN
Screening of the endothelin1 gene (EDN1) in a cohort of patients with essential left ventricular hypertrophy.
17335511
2007
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Biomarker
phenotype
RGD
Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy.
17487232
2006
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Biomarker
phenotype
CTD_human
Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy.
17487232
2006
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Therapeutic
phenotype
CTD_human
Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy.
17487232
2006
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Biomarker
phenotype
CTD_human
Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure.
16844920
2006
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Therapeutic
phenotype
CTD_human
Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure.
16844920
2006
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Biomarker
phenotype
CTD_human
Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion.
12224825
2002
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Therapeutic
phenotype
CTD_human
Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion.
12224825
2002
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Therapeutic
phenotype
CTD_human
Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene inhibits protein synthesis of rat ventricular cardiomyocytes.
11504159
2001
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.510
Biomarker
phenotype
CTD_human
Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene inhibits protein synthesis of rat ventricular cardiomyocytes.
11504159
2001
×
Entrez Id:
1906
Gene Symbol:
EDN1
EDN1
0.510
ModifyingMutation
phenotype
RGD
Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy.
7771559
1995
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Biomarker
phenotype
CTD_human
Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1α signaling.
31016362
2019
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Biomarker
phenotype
CTD_human
Irisin attenuates angiotensin II-induced cardiac fibrosis via Nrf2 mediated inhibition of ROS/ TGFβ1/Smad2/3 signaling axis.
30703374
2019
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Therapeutic
phenotype
CTD_human
Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1α signaling.
31016362
2019
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Therapeutic
phenotype
CTD_human
Irisin attenuates angiotensin II-induced cardiac fibrosis via Nrf2 mediated inhibition of ROS/ TGFβ1/Smad2/3 signaling axis.
30703374
2019
×
Entrez Id:
488
Gene Symbol:
ATP2A2
ATP2A2
0.500
Therapeutic
phenotype
RGD
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
29792884
2018
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Therapeutic
phenotype
CTD_human
Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway.
29353218
2018
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Biomarker
phenotype
CTD_human
Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway.
29353218
2018
×
Entrez Id:
9464
Gene Symbol:
HAND2
HAND2
0.500
Biomarker
phenotype
CTD_human
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.
29394407
2018
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Therapeutic
phenotype
CTD_human
SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity.
27099261
2017
×
Entrez Id:
9927
Gene Symbol:
MFN2
MFN2
0.500
Therapeutic
phenotype
RGD
Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats.
27847271
2017
×
Entrez Id:
183
Gene Symbol:
AGT
AGT
0.500
Biomarker
phenotype
CTD_human
SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity.
27099261
2017