Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Biomarker disease BEFREE Higher IL-10 concentration among patients free of cardiovascular events could be a reflection of its anti-inflammatory and thus protective role in HF. 30795907 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Biomarker disease RGD This study examined the effects of exercise training (ExT) upon concentration of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and interleukin-10 (IL-10) in the gastrocnemius of rats with heart failure (HF) induced by left coronary artery ligation. 28939262 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 AlteredExpression disease BEFREE The percentage of human leukocyte antigen-D-related (HLA-DR)<sup>-</sup>CD33<sup>+</sup>CD11b<sup>+</sup> MDSCs in the blood of patients with HF was significantly increased and positively correlated with disease severity and increased plasma levels of cytokines, including interleukin-6, interleukin-10, and transforming growth factor-β. 29437117 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Biomarker disease BEFREE Our results also demonstrated a direct correlation of IL-10 with the ejection fraction in patients with MI: IL-10 was elevated in MI+NEF group, however, the levels were significantly low in MI+LEF group suggesting an important role of IL-10 in predicting heart failure. 30356307 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Biomarker disease BEFREE To describe correlations and agreement between salivary and serum B-type natriuretic peptide (BNP), C-reactive protein (CRP), interleukin (IL)-6, and IL-10 and determine which biomarkers predict worse functional class in patients with heart failure (HF). 27605566 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 AlteredExpression disease BEFREE Moreover, the pro- and anti-inflammatory cytokines interferon (IFN)-γ, interleukin (IL)-6 and IL-10 in patients with CHF also demonstrated an increased expression within its pericardial fluid. 28565777 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Biomarker disease BEFREE Interleukin-1b (IL-1b) and interleukin-10 (IL-10) biomarkers are one of many antigens that are secreted in acute stages of inflammation after left ventricle assisted device (LVAD) implantation for patients suffering from heart failure (HF). 27660015 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Therapeutic disease RGD Aerobic exercise improves the inflammatory profile correlated with cardiac remodeling and function in chronic heart failure rats. 23778495 2013
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 ModifyingMutation disease RGD We tested whether a decrease in the ratio of interleukin-10 (IL-10) to tumor necrosis factor-alpha (TNF-alpha) correlates with the decrease in cardiac function in heart failure. 16461369 2006
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 GeneticVariation disease BEFREE No association between IL-10 promoter gene polymorphism and heart failure or rejection following cardiac transplantation. 11260510 2001
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.280 Biomarker disease BEFREE Serum concentrations of IL-2, IL-4, IL-10, and IL-12 were measured in patients with DCM (WHO criteria), relatives with asymptomatic left ventricular enlargement (LVE), patients with ischaemic heart failure (IHD), and healthy controls. 8800994 1996