Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.160 | GeneticVariation | disease | BEFREE | Several studies have focused on the association between KIF1B rs17401966 polymorphism and susceptibility to hepatitis B virus-related (HBV-related) hepatocellular carcinoma (HCC), but the conclusions have been inconsistent. | 30947687 | 2019 | ||||
|
0.160 | Biomarker | disease | BEFREE | Many GWASs conclude that the genetic variants in the HLA region (HLA-DP, HLA-DQ, HLA-DR and MICA), KIF1B, DEPDC5 and PNPLA3 influence HBV infection, its clinical course and the response to hepatitis B vaccination. | 25475418 | 2015 | ||||
|
0.160 | Biomarker | disease | BEFREE | This study showed the new locus identified for HCC, KIF1B, was not associated with progression to CHB, implying distinct genetic susceptibility factor contributes to the progression from hepatitis B virus infection to HCC. | 22363396 | 2012 | ||||
|
0.160 | GeneticVariation | disease | BEFREE | A recent genome wide association study (GWAS) study conducted on a Chinese population has reported the involvement of a KIF1B genetic variant in Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). | 23028799 | 2012 | ||||
|
0.160 | GeneticVariation | disease | BEFREE | A recent genome-wide association study (GWAS) using chronic HBV (hepatitis B virus) carriers with and without hepatocellular carcinoma (HCC) in five independent Chinese populations found that one SNP (rs17401966) in KIF1B was associated with susceptibility to HCC. | 22712471 | 2012 | ||||
|
0.160 | GeneticVariation | disease | BEFREE | Genome-wide association studies (GWAS) have recently identified KIF1B as susceptibility locus for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). | 22807686 | 2012 | ||||
|
0.160 | GeneticVariation | disease | GWASDB | A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. | 21750111 | 2011 |