| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | AlteredExpression | disease | BEFREE | Hepatitis B virus X protein decreases nephrin expression and induces podocyte apoptosis via activating STAT3. | 31007753 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Interestingly, we show that during early HBV infection, p38 mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription 3 (STAT3) were activated to facilitate HBV replication; however, during late HBV infection, HoxA10 was induced to attenuate HBV replication. | 30674631 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Previously, we showed that hepatitis B virus (HBV) large surface protein (LHB) variant W4P promotes carcinogenesis and tumor progression through STAT3 activation. | 29953997 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The association between polymorphism rs1053005 and haplotypes formed by rs1053004 and rs1053005 in the 3'UTR of STAT3 and chronic HBV infection has yet to be investigated. | 29609539 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | These results illustrate that perhaps rs1053004 polymorphisms in the STAT3 gene participated in the progression of hepatitis B to HCC in Iranian people. | 29307341 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | The roles of STAT3 and HK-II in hepatitis B virus (HBV)- and hepatitis C virus (HCV)-related HCC remain largely unclear. | 26889748 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Interaction of signal transducer and activator of transcription 3 polymorphisms with hepatitis B virus mutations in hepatocellular carcinoma. | 23386590 | 2013 | ||||
|
0.090 | Biomarker | disease | BEFREE | Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3. | 20447714 | 2010 | ||||
|
0.090 | Biomarker | disease | BEFREE | We have identified a STAT-3 binding site within the core domain of hepatitis B virus (HBV) enhancer 1. | 11861839 | 2002 |