| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | AlteredExpression | disease | BEFREE | Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes. | 12824191 | 2003 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | Successfully inducing anti-E2 antibody in mice by plasmid DNA-based immunization containing E2/NS1 gene from a Chinese genotype III/2a isolate of HCV is the first time in China. | 11593587 | 1999 | ||||
|
0.100 | Biomarker | disease | BEFREE | The variability of E2/NS1 gene should be taken into account in the development of vaccine against HCV in China. | 11155671 | 1998 | ||||
|
0.100 | Biomarker | disease | BEFREE | Analysis of the hypervariable region of hepatitis C virus E2/NS1 gene in an infant infected by blood transfusion. | 9262231 | 1997 | ||||
|
0.100 | Biomarker | disease | BEFREE | The E2/NS1 gene of HCV encoding the amino acid sequence 388-664 was molecularly cloned into a vector containing an SV 40 promotor and was expressed in Chinese Hamster ovary cells. | 8959633 | 1996 | ||||
|
0.100 | Biomarker | disease | BEFREE | Nucleotide sequences of the hypervariable region (HVR) of the E2/NS1 gene of hepatitis C virus (HCV), which are now thought to contain epitopes for neutralizing antibodies, were compared between antibody-bound HCV and free HCV in a patient with type II cryoglobulinemia. | 7595420 | 1995 | ||||
|
0.100 | Biomarker | disease | BEFREE | Differential pattern of sequence heterogeneity in the hepatitis C virus E1 and E2/NS1 proteins. | 7534322 | 1994 | ||||
|
0.100 | Biomarker | disease | BEFREE | We conclude that genotypic variability within the E2/NS1 gene of HCV results in antigenically distinct variants. | 7689636 | 1993 | ||||
|
0.100 | Biomarker | disease | BEFREE | A structurally flexible and antigenically variable N-terminal domain of the hepatitis C virus E2/NS1 protein: implication for an escape from antibody. | 7686313 | 1993 | ||||
|
0.100 | Biomarker | disease | BEFREE | Detection of antibody to hepatitis C E2/NS1 protein in patients with type C hepatitis. | 1280430 | 1992 |