Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1 		0.500 Biomarker phenotype CTD_human Effects of antioxidant vitamins on molecular regulators involved in lung hypoplasia induced by nitrofen. 16863852 2006
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3 		0.500 Biomarker phenotype MGD A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3. 12702769 2003
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3 		0.500 Biomarker phenotype MGD Slit3-deficient mice represent a genetic animal model for physiological and pathological studies of congenital diaphragmatic hernia. 14550534 2003
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.500 Biomarker phenotype RGD Gene expression of insulin-like growth factor-1 and epidermal growth factor is downregulated in the heart of rats with nitrofen-induced diaphragmatic hernia. 11409163 2001
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.500 Biomarker phenotype CTD_human Administration of antenatal glucocorticoids upregulates peptide growth factor gene expression in nitrofen-induced congenital diaphragmatic hernia in rats. 10646786 2000
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1 		0.500 Biomarker phenotype CTD_human Down-regulation of thyroid transcription factor-1 gene expression in fetal lung hypoplasia is restored by glucocorticoids. 10830305 2000
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.500 Biomarker phenotype CTD_human Antenatal dexamethasone suppresses tumor necrosis factor-alpha expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats. 10541330 1999
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.500 Biomarker phenotype CTD_human Effect of antenatal glucocorticoid administration on insulin-like growth factor I and II levels in hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia in rats. 10370016 1999
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.500 Biomarker phenotype CTD_human Effect of antenatal glucocorticoid administration on insulin-like growth factor I and II levels in hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia in rats. 10370016 1999
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.500 Biomarker phenotype RGD Antenatal dexamethasone suppresses tumor necrosis factor-alpha expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats. 10541330 1999
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.500 Biomarker phenotype CTD_human Decreased pulmonary nitric oxide synthase activity in the rat model of congenital diaphragmatic hernia. 8863223 1996
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.500 Biomarker phenotype CTD_human Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia. 7576705 1995
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.500 Biomarker phenotype RGD Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia. 7576705 1995
Entrez Id: 7026
Gene Symbol: NR2F2
NR2F2 		0.500 Biomarker phenotype MGD
Entrez Id: 4036
Gene Symbol: LRP2
LRP2 		0.310 GeneticVariation phenotype BEFREE Mutations in LRP2 have been shown to cause the Donnai-Barrow syndrome (DBS) or facio-oculo-acoustico-renal (FOAR) syndrome, a syndrome associated with facial dysmorphism, ocular anomalies, sensorineural hearing loss, low molecular weight proteinuria, and diaphragmatic hernia and absent corpus callosum, although there is variability in the expression of some features. 23992033 2014
Entrez Id: 64220
Gene Symbol: STRA6
STRA6 		0.310 GeneticVariation phenotype LHGDN Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation. 17273977 2007
Entrez Id: 4036
Gene Symbol: LRP2
LRP2 		0.310 Biomarker phenotype CTD_human Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes. 17632512 2007
Entrez Id: 64220
Gene Symbol: STRA6
STRA6 		0.310 Biomarker phenotype CTD_human Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation. 17273977 2007
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.310 Biomarker phenotype CTD_human Altered renin-angiotensin system gene expression causes renal hypoplasia in the rats with nitrofen-induced diaphragmatic hernia. 16292651 2006
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.310 GeneticVariation phenotype LHGDN Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension. 15017542 2004
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1 		0.300 Biomarker phenotype CTD_human Abnormal development of tracheal innervation in rats with experimental diaphragmatic hernia. 18958481 2008
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker phenotype CTD_human Intrinsic catch-up growth of hypoplastic fetal lungs is mediated by interleukin-6. 18500730 2008
Entrez Id: 3213
Gene Symbol: HOXB3
HOXB3 		0.300 Biomarker phenotype CTD_human [The etiology of congenital diaphragmatic hernia and esophageal atresia: the Hox genes]. 18351244 2007
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.300 Biomarker phenotype CTD_human Impaired alveolar epithelial cell differentiation in the hypoplastic lung in nitrofen-induced congenital diaphragmatic hernia. 17245593 2007
Entrez Id: 3202
Gene Symbol: HOXA5
HOXA5 		0.300 Biomarker phenotype CTD_human [The etiology of congenital diaphragmatic hernia and esophageal atresia: the Hox genes]. 18351244 2007