Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 81622
Gene Symbol: UNC93B1
UNC93B1 		0.020 GeneticVariation group LHGDN Herpes simplex virus encephalitis in human UNC-93B deficiency. 16973841 2006
Entrez Id: 941
Gene Symbol: CD80
CD80 		0.020 AlteredExpression group LHGDN Augmentation of B7 expression by herpes simplex virus antigen. 12878356 2003
Entrez Id: 10014
Gene Symbol: HDAC5
HDAC5 		0.020 Biomarker group LHGDN Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. 15194749 2004
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4 		0.020 Biomarker group LHGDN Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. 15194749 2004
Entrez Id: 29843
Gene Symbol: SENP1
SENP1 		0.020 Biomarker group LHGDN Herpes simplex virus 1 ICP0 co-localizes with a SUMO-specific protease. 12466471 2002
Entrez Id: 8651
Gene Symbol: SOCS1
SOCS1 		0.020 AlteredExpression group LHGDN Molecular analysis of human cancer cells infected by an oncolytic HSV-1 reveals multiple upregulated cellular genes and a role for SOCS1 in virus replication. 18551144 2008
Entrez Id: 2965
Gene Symbol: GTF2H1
GTF2H1 		0.010 Biomarker group LHGDN NMR structure of the amino-terminal domain from the Tfb1 subunit of TFIIH and characterization of its phosphoinositide and VP16 binding sites. 15909982 2005
Entrez Id: 6404
Gene Symbol: SELPLG
SELPLG 		0.010 AlteredExpression group LHGDN Expression of cutaneous lymphocyte-associated antigen by CD8(+) T cells specific for a skin-tropic virus. 12189248 2002
Entrez Id: 545
Gene Symbol: ATR
ATR 		0.010 Biomarker group LHGDN Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection. 16757521 2006
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		0.010 Biomarker group LHGDN Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. 15194749 2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.010 Biomarker group LHGDN The present study was undertaken to investigate whether transforming growth factor-beta (TGF-beta) isoforms (TGF-beta1, TGF-beta2, and TGF-beta3) and SMADs (SMAD2 and SMAD3) are involved in herpes simplex virus type 1 (HSV-1) corneal infection. 18776948 2008
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA 		0.010 Biomarker group LHGDN Herpes simplex virus disrupts NF-kappaB regulation by blocking its recruitment on the IkappaBalpha promoter and directing the factor on viral genes. 16407234 2006
Entrez Id: 4691
Gene Symbol: NCL
NCL 		0.010 Biomarker group LHGDN Using small interfering RNA technology, we show that viral replication requires a high level of nucleolin expression, demonstrating for the first time a direct role for a nucleolar protein in herpes simplex virus biology. 18321972 2008
Entrez Id: 7520
Gene Symbol: XRCC5
XRCC5 		0.010 Biomarker group LHGDN A human cellular protein activity (OF-1), which binds herpes simplex virus type 1 origin, contains the Ku70/Ku80 heterodimer. 15220460 2004
Entrez Id: 4001
Gene Symbol: LMNB1
LMNB1 		0.010 Biomarker group LHGDN Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane. 18524819 2008
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.010 Biomarker group LHGDN HSV-1 infection suppresses TGF-beta1 and SMAD3 expression in human corneal epithelial cells. 18776948 2008
Entrez Id: 2547
Gene Symbol: XRCC6
XRCC6 		0.010 Biomarker group LHGDN A human cellular protein activity (OF-1), which binds herpes simplex virus type 1 origin, contains the Ku70/Ku80 heterodimer. 15220460 2004
Entrez Id: 9451
Gene Symbol: EIF2AK3
EIF2AK3 		0.010 AlteredExpression group LHGDN Here we show that HSV infection also induces phosphorylation of an endoplasmic reticulum (ER) resident kinase PERK, a hallmark of ER stress response. 15650164 2005
Entrez Id: 51652
Gene Symbol: CHMP3
CHMP3 		0.010 AlteredExpression group LHGDN By expression of dominant negative forms of Vps4 and Vps24, two components of the MVB pathway, we observed an impairment in infectious herpes simplex virus (HSV) assembly/egress, in agreement with a recent report showing the involvement in HSV envelopment of Vps4, the MVB-specific ATPase (C. M. Crump, C. Yates, and T. Minson, J. Virol.81:7380-7387). 17686835 2007
Entrez Id: 22879
Gene Symbol: MON1B
MON1B 		0.010 Biomarker group LHGDN Identification of a novel human sand family protein in human fibroblasts induced by herpes simplex virus 1 binding. 12828340 2003
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		0.010 Biomarker group LHGDN Effects of lamin A/C, lamin B1, and viral US3 kinase activity on viral infectivity, virion egress, and the targeting of herpes simplex virus U(L)34-encoded protein to the inner nuclear membrane. 18524819 2008
Entrez Id: 64711
Gene Symbol: HS3ST6
HS3ST6 		0.010 Biomarker group LHGDN Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1. 12138164 2002
Entrez Id: 28996
Gene Symbol: HIPK2
HIPK2 		0.010 Biomarker group LHGDN US11 of herpes simplex virus type 1 interacts with HIPK2 and antagonizes HIPK2-induced cell growth arrest. 14990717 2004
Entrez Id: 942
Gene Symbol: CD86
CD86 		0.010 AlteredExpression group LHGDN Augmentation of B7 expression by herpes simplex virus antigen. 12878356 2003
Entrez Id: 3337
Gene Symbol: DNAJB1
DNAJB1 		0.010 Biomarker group LHGDN Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection. 15194794 2004