Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 25824
Gene Symbol: PRDX5
PRDX5
0.010 AlteredExpression disease BEFREE An upregulated expression of Prdx3 and Prdx5 has been reported in different cancer types, such as breast, ovarian, endometrial, and lung cancers, as well as in Hodgkin's lymphoma and hepatocellular carcinoma. 31500275 2019
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
0.010 AlteredExpression disease BEFREE Validation of proteins implicated in sperm fertility potential by Western Blot demonstrated that peroxiredoxin 2 (PRDX 2) was underexpressed (p=0.015), and transferrin (p=0.045) and SERPIN A5 (p=0.010) protein levels were overexpressed in spermatozoa of men with HD. 31385466 2019
Entrez Id: 57591
Gene Symbol: MRTFA
MRTFA
0.010 AlteredExpression disease BEFREE While cells from the Hodgkin lymphoma treated patients had a phenotype close to healthy controls, cells from the undiagnosed triplet had increased MKL1 mRNA, increased MKL1 protein, and elevated expression of MKL1-dependent genes. 31582539 2019
Entrez Id: 55783
Gene Symbol: CMTR2
CMTR2
0.010 Biomarker disease BEFREE Considering Cox and three parametric event-time models, the parametric AFT log-normal had the best efficiency in determining factors influencing HD patients survival. 31185926 2019
Entrez Id: 407
Gene Symbol: ARR3
ARR3
0.010 Biomarker disease BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631 2019
Entrez Id: 7218
Gene Symbol: TRP-AGG2-6
TRP-AGG2-6
0.010 Biomarker disease BEFREE In accordance, cortisol level tended to be higher in fish fed both supplemented diets at LD compared to fish fed CTRL, but was lower in fish fed TRP4 than in those fed TRP2 under HD condition. 31118899 2019
Entrez Id: 846
Gene Symbol: CASR
CASR
0.010 Biomarker disease BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631 2019
Entrez Id: 151176
Gene Symbol: ERFE
ERFE
0.010 Biomarker disease BEFREE Serum ERFE is associated with mortality and CV events in CKD and in HD patients, and treatment by ESA amplifies the risk for this combined end-point in HD patients. 30995819 2019
Entrez Id: 5903
Gene Symbol: RANBP2
RANBP2
0.010 Biomarker disease BEFREE In accordance, cortisol level tended to be higher in fish fed both supplemented diets at LD compared to fish fed CTRL, but was lower in fish fed TRP4 than in those fed TRP2 under HD condition. 31118899 2019
Entrez Id: 5309
Gene Symbol: PITX3
PITX3
0.010 Biomarker disease BEFREE PTX-3 increased only in HD patients and was highest at M0, and it then gradually decreased. 30952879 2019
Entrez Id: 693122
Gene Symbol: MIR421
MIR421
0.010 AlteredExpression disease BEFREE In this study, we investigated the correlation between serum levels of miR-421 and ACE2 transcripts in circulating leukocytes of healthy individuals (NP), CKD (3-5) and haemodialysis (HD) patients. 30326474 2019
Entrez Id: 10999
Gene Symbol: SLC27A4
SLC27A4
0.010 GeneticVariation disease BEFREE Prognostic Utility of the IPS 3 Score for Predicting Outcomes in Advanced Hodgkin Lymphoma. 30579722 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.010 AlteredExpression disease BEFREE Serum osteopontin level is associated with heart valve calcification in HD patients, but there was no relationship found with FGF-23. 30369401 2019
Entrez Id: 5091
Gene Symbol: PC
PC
0.010 Biomarker disease BEFREE Our results suggest that PC and PS deficiencies may be related to survival in HD patients. 31138132 2019
Entrez Id: 2671
Gene Symbol: GFER
GFER
0.010 Biomarker disease BEFREE We generated phenotype-disease bipartite graphs for HPO-Orphanet, EMR, and enriched knowledge base HPO-Orphanet + and conducted a case study on Hodgkin lymphoma to compare performance on differential diagnosis among these three graphs. 30764825 2019
Entrez Id: 3111
Gene Symbol: HLA-DOA
HLA-DOA
0.010 AlteredExpression disease BEFREE Of note, brentuximab vedotin is an antibody-drug conjugate that targets CD30, another lymphocyte antigen expressed on the cell surface of both Hodgkin lymphoma (a variant of B-cell lymphoma) and some T-cell lymphomas. 31580408 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.010 GeneticVariation disease BEFREE A total thyroidectomy with bilateral lymph node dissection was performed and the microscopic examination revealed a 2-cm PTC with BRAF mutation and HL (mixed cellularity) in the bilateral lymph nodes. 30653166 2019
Entrez Id: 3683
Gene Symbol: ITGAL
ITGAL
0.010 AlteredExpression disease BEFREE Interestingly, cells from the triplet treated for Hodgkin lymphoma in 1985 contained two subpopulations: one with high expression of CD11a that behaved like control cells and the other with low expression of CD11a that formed large tumors in vivo similar to cells from the undiagnosed triplet. 31582539 2019
Entrez Id: 6687
Gene Symbol: SPG7
SPG7
0.010 Biomarker disease BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631 2019
Entrez Id: 653108
Gene Symbol: CXADRP1
CXADRP1
0.010 Biomarker disease BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631 2019
Entrez Id: 5971
Gene Symbol: RELB
RELB
0.010 Biomarker disease BEFREE BCL2 was exclusively controlled by Rel-B in HL. 30941572 2019
Entrez Id: 51477
Gene Symbol: ISYNA1
ISYNA1
0.010 GeneticVariation disease BEFREE Prognostic Utility of the IPS 3 Score for Predicting Outcomes in Advanced Hodgkin Lymphoma. 30579722 2019
Entrez Id: 3929
Gene Symbol: LBP
LBP
0.010 AlteredExpression disease BEFREE Our aim is to investigate the relationship between circulating levels of LBP, and various metabolic and inflammatory markers in HD patients. 30219816 2019
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
0.010 Biomarker disease BEFREE This review focuses on application of CAR-T cells in hematologic malignancies beyond targeting CD19, with specific attention to Hodgkin's lymphoma and acute myeloid leukemia. 30632631 2019
Entrez Id: 192142
Gene Symbol: RLS1
RLS1
0.010 Biomarker disease BEFREE Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a common sensorimotory disorder affecting almost 30% of hemodialysis (HD) patients. 28682991 2018