| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.360 | Biomarker | disease | CTD_human | Tissue microarray analysis of primary Hodgkin lymphomas displayed that 82% cases (95/116) expressed cFLIP in Reed-Sternberg cells. | 17659339 | 2008 | ||||
|
0.360 | Biomarker | disease | BEFREE | Both ATM and FLIP are aberrantly regulated in Hodgkin lymphoma. | 17932249 | 2008 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | Tissue microarray analysis of primary Hodgkin lymphomas displayed that 82% cases (95/116) expressed cFLIP in Reed-Sternberg cells. | 17659339 | 2008 | ||||
|
0.360 | Biomarker | disease | BEFREE | In this review, the role of cellular FLICE-like inhibitory protein in the pathogenesis of Hodgkin's lymphoma will be explored and also the possibility of targeting this molecule in order to provide an alternative and potentially safe approach to the treatment of Hodgkin's lymphoma will be investigated. | 16761935 | 2006 | ||||
|
0.360 | Biomarker | disease | LHGDN | The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer. | 16441226 | 2006 | ||||
|
0.360 | AlteredExpression | disease | LHGDN | In conclusion, we detected c-FLIP in a significantly lower proportion of nodular lymphocyte-predominant Hodgkin lymphoma cases compared with classic Hodgkin lymphoma cases. | 15354734 | 2004 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | However, strong c-FLIP expression in nodular lymphocyte-predominant Hodgkin lymphoma was associated with transformation to large B-cell lymphoma in 2 cases. c-FLIP expression is not limited to Hodgkin lymphoma, because the majority of diffuse large B-cell lymphoma cases tested were strongly c-FLIP-positive. | 15354734 | 2004 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | In one of the two cases with loss of heterozygosity a hemizygous mutation was detected in exon 9. c-FLIP expression was observed in all HL cell lines and in RS cells of all HL cases. | 12507887 | 2003 |