Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | phenotype | BEFREE | Because prolonged starvation has been shown to increase AgRP and NPY, the expression level of these two orexigenic genes has been taken as an experimental readout for the presence or absence of hunger. | 30718818 | 2019 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | Neuropeptides at the crossroad of fear and hunger: a special focus on neuropeptide Y. | 31271235 | 2019 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | These findings reveal a unique role for NPY in sustaining hunger in the interval between food discovery and consumption. | 31033437 | 2019 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | To trigger hunger signaling, neuropeptide Y activates a group of neurons in the paraventricular hypothalamic nucleus (PVH), which then stimulate an excitatory pathway to the medullary circuit to drive the hunger responses. | 29869415 | 2018 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | AgRP neurons, which also co-produce neuropeptide Y (NPY) and γ-Aminobutyric acid (GABA), are involved in an increase in hunger and a decrease in energy expenditure. | 30012460 | 2018 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | Hypothalamic neuropeptide Y (NPY) elicits hunger responses to increase the chances of surviving starvation: an inhibition of metabolism and an increase in feeding. | 28065829 | 2017 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | Stress-induced suppression of neuropeptide Y-induced hunger in anorexic chicks involves corticotrophin-releasing factor signalling and the paraventricular nucleus of the hypothalamus. | 29121414 | 2017 | ||||
|
0.080 | GeneticVariation | phenotype | BEFREE | Dietary restraint and disinhibition were associated with an SNP in GHSR (477G>A, P<0.05), and perceived hunger with SNPs in GHSR and NPY (477G>A and 204T>C, P<0.05). | 18957934 | 2008 |