Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.250 Biomarker disease BEFREE Here, we investigated the beneficial effects of Y2 receptor (Y2R) activation with NPY or Y2R selective agonist NPY<sub>13-36</sub> in the R6/2 mouse and PC12 cell models of HD. 29309751 2018
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.250 Biomarker disease BEFREE Thus, NPY might act through Y2 receptors to slow down the course of HD, and hence, this peptide could be of interest as a possible therapeutic agent. 24121255 2014
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.250 Biomarker disease BEFREE Loss of CB(1) signaling in NPY/nNOS-expressing interneurons could contribute to the impairment of basal ganglia functions linked to HD. 23167744 2013
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.250 Biomarker disease LHGDN NPY and chronic neurodegenerative disease. 16383010 2006
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.250 Biomarker disease BEFREE The results described here suggest that although the population of interneurons containing somatostatin, neuropeptide Y and neuronal nitric oxide synthase do survive in the striatum in Huntington's disease they are damaged during the course of the disease. 8735228 1996
Entrez Id: 4852
Gene Symbol: NPY
NPY
0.250 Biomarker disease RGD Chronic QA lesions therefore closely resemble the neurochemical features of HD, because they result in increases in somatostatin and neuropeptide Y and in 5-HT and HIAA. 1710657 1991