Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease BEFREE In this study, we examined the differences in leptin, leptin receptor, total cholesterol, and triglyceride levels between healthy dogs and dogs with cholelithiasis, and evaluated the correlation between leptin and hyperlipidemia. 29088261 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 GeneticVariation disease BEFREE Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia. 26984935 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 GeneticVariation disease BEFREE We investigated the associations of <i>LEP G2548A</i> and <i>LEPR Q223R</i> polymorphisms with statin-induced creatine kinase (CK) elevation among Chinese patients with hyperlipidemia. 29296187 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease RGD Change in lipid components in the adipose and liver tissues of regucalcin transgenic rats with increasing age: suppression of leptin and adiponectin gene expression. 17671736 2007
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease BEFREE In this child, 4 yr of therapy with sc injections of recombinant leptin provided additional evidence for the sustained beneficial effects of leptin replacement on fat mass, hyperinsulinemia, and hyperlipidemia. 15472169 2004
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease BEFREE Three morbidly obese children, who were congenitally deficient in leptin, were treated with daily subcutaneous injections of recombinant human leptin for up to 4 years with sustained, beneficial effects on appetite, fat mass, hyperinsulinemia, and hyperlipidemia. 12393845 2002