| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | disease | BEFREE | The multivariable risk factors for CAD were hypertension (odds ratio [ OR ] 2.14; 95% CI 1.36-3.38), hyperlipidemia ( OR 3.33; 95% CI 2.02-5.47), diabetes mellitus ( OR 1.98; 95% CI 1.31-3.61), male sex ( OR 2.05; 95% CI 1.33-3.17), and older age per year ( OR 1.06; 95% CI 1.04-1.07). | 31195876 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | The inverse correlation between common vascular risk factors (i.e. hypertension and hyperlipidemia) and CAD points to CAD as an independent nonatherosclerotic causative factor in the etiology of acute ischemic stroke. | 28920508 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | They include similar risk factors for the development of CAD To increase the likelihood of determining CAD severity, the CHA2DS2-VASc-HS and CHA2DS2-VASc-HSF score comprising of hyperlipidemia, smoking and family history respectively in addition to the components of the CHA2DS2-VASc score and male instead of female gender. | 27915215 | 2017 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | For the XbaI polymorphism, after controlling for age, male sex, cigarette smoking and hyperlipidemia, XbaI GG genotype was not also found to be an independent predictor for CAD occurrence (OR=1.65; 95% CI: 0.90-3.03; P=0.10). | 19318036 | 2009 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Hyperlipidemia was found in 68% of patients with CAD, of their first-degree relatives, and 24% of controls. | 7818160 | 1995 | ||||
|
0.070 | Biomarker | disease | BEFREE | The recently completed NHLBI sponsored multicenter double-blind Coronary Heart Disease Prevention Trial has provided the long sought-after proof that hyperlipidemia is a major CAD risk factor and that the incidence of CHD and its complications can be favorable modified by control of hyperlipidemia with appropriate diet-drug therapy. | 3873080 | 1985 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The chance of identifying a child with hyperlipidemia was three times greater if the father had premature CAD. | 1185418 | 1975 |