Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 130120
Gene Symbol: REG3G
REG3G 		0.300 Biomarker group CTD_human Mitogen-activated protein kinase p38 target regenerating islet-derived 3γ expression is upregulated in cardiac inflammatory response in the rat heart. 27798352 2016
Entrez Id: 4615
Gene Symbol: MYD88
MYD88 		0.300 Biomarker group CTD_human Our findings suggest that TLR4/MyD88/NF-κB signaling and PPAR-γ within the PVN are involved in the beneficial effects of telmisartan in hypertension. 27292124 2016
Entrez Id: 4057
Gene Symbol: LTF
LTF 		0.300 Therapeutic group CTD_human Antioxidant effects of bovine lactoferrin on dexamethasone-induced hypertension in rat. 24587916 2014
Entrez Id: 10928
Gene Symbol: RALBP1
RALBP1 		0.300 Biomarker group CTD_human RLIP76 protein knockdown attenuates obesity due to a high-fat diet. 23821548 2013
Entrez Id: 486
Gene Symbol: FXYD2
FXYD2 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1 		0.300 Biomarker group CTD_human Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. 22949532 2012
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2 		0.300 Biomarker group CTD_human Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole. 22352330 2012
Entrez Id: 27020
Gene Symbol: NPTN
NPTN 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 221357
Gene Symbol: GSTA5
GSTA5 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 2811
Gene Symbol: GP1BA
GP1BA 		0.300 Biomarker group CTD_human Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole. 22352330 2012
Entrez Id: 475
Gene Symbol: ATOX1
ATOX1 		0.300 Therapeutic group CTD_human Antioxidant 1 (Atox1) is shown to act as a copper-dependent transcription factor, as well as a copper chaperone, for SOD3 in vitro, but its role in Ang II-induced hypertension in vivo is unknown. 22753205 2012
Entrez Id: 7168
Gene Symbol: TPM1
TPM1 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 2953
Gene Symbol: GSTT2
GSTT2 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 9445
Gene Symbol: ITM2B
ITM2B 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 4190
Gene Symbol: MDH1
MDH1 		0.300 Biomarker group CTD_human A custom rat and baboon hypertension gene array to compare experimental models. 22228705 2012
Entrez Id: 5624
Gene Symbol: PROC
PROC 		0.300 Biomarker group CTD_human Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole. 22352330 2012
Entrez Id: 63036
Gene Symbol: CELA2A
CELA2A 		0.300 Biomarker group CTD_human Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme. 21602471 2011
Entrez Id: 10052
Gene Symbol: GJC1
GJC1 		0.300 Therapeutic group CTD_human The high blood pressure of the Cx40 knockout mice was significantly reduced when Cx45 was knocked into the locus but remained mildly elevated compared to wild-type mice. 19109587 2009
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1 		0.300 Biomarker group CTD_human Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1. 19289642 2009
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1 		0.300 Biomarker group CTD_human Angiotensin II-induced hypertension altered vascular glutathione flux by increasing GSSG export and decreasing vascular levels of glutathione in wild-type (FVB) but not in MRP1-/- mice. 17272743 2007
Entrez Id: 5473
Gene Symbol: PPBP
PPBP 		0.300 Biomarker group CTD_human Platelet morphology and plasma indices of platelet activation in essential hypertension: effects of amlodipine-based antihypertensive therapy. 15513305 2004
Entrez Id: 4158
Gene Symbol: MC2R
MC2R 		0.300 Biomarker group CTD_human Functional adrenocorticotropic hormone receptor in cultured human vascular endothelial cells : possible role in control of blood pressure. 11082157 2000
Entrez Id: 1908
Gene Symbol: EDN3
EDN3 		0.300 Biomarker group CTD_human Effects of endothelin 3 on diastolic blood pressure of pithed Sprague-Dawley, Wistar Kyoto, and spontaneously hypertensive rats before and after pretreatment with nifedipine. 2059916 1991
Entrez Id: 5473
Gene Symbol: PPBP
PPBP 		0.300 Biomarker group CTD_human Increased beta-thromboglobulin in essential hypertension: interactions between arterial plasma adrenaline, platelet function and blood lipids. 6192689 1983
Entrez Id: 2796
Gene Symbol: GNRH1
GNRH1 		0.300 Biomarker group CTD_human In addition, intraventricular administration of TRH, LHRH or LH caused tachycardia, hypertension and a reduction in the epinephrine-induced reflex bradycardia. 6350720 1983