Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE OmniHeart was a randomized 3-period, crossover feeding study in 164 adults with high blood pressure or hypertension (SBP 120-159 or DBP 80-99 mm Hg). 31447226 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Both the ENSs' and AHNSs' groups: (a) had similar values of FBG (5.38 ± 0.58 vs. 5.60 ± 0.37), TC (4.87 ± 1.16 vs. 4.36 ± 0.74), HDL-C (0.92 ± 0.30 vs. 0.82 ± 0.21), LDL-C (3.09 ± 0.98 vs. 2.92 ± 0.77), SBP (117 ± 9 vs. 115 ± 8), and DBP (76 ± 6 vs. 73 ± 7); and (b) included similar percentages of males having normal weight (17.2% vs. 31.0%); overweight (44.8% vs. 62.1%); android obesity (79.3% vs. 59.6%), hypertension (10.3% vs. 10.3%), hyperglycemia (37.9% vs. 48.2%), and MetS (51.7% vs. 34.5%). 30819065 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE When trials were limited to those involving subjects with hypertension, the WMD in RBP decreased significantly [RSBP: - 5.6 mmHg (95% CI - 9.1 to - 2.1); RDBP: - 5.2 mmHg (95% CI - 9.0 to - 1.4)] but contained significant heterogeneity (RSBP: P = 0.01, I<sup>2</sup> = 62.2%; DBP: P < 0.01, I<sup>2</sup> = 87.7) and a meta-regression analysis showed that the percentage of maximum heart rate was significantly associated with the WMD in RSBP [slope: 0.56 (95% CI 0.21 to 0.92), intercept: - 48.76 (95% CI - 76.30 to - 21.22), R<sup>2</sup> = 0.88] and RDBP [slope: 0.45 (95% CI 0.01 to 0.87), intercept: - 38.06 (95% CI - 72.30 to - 4.08), R<sup>2</sup> = 0.41]. 31677122 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Both DBP and systolic blood pressure were associated with incident ASCVD, myocardial infarction, and stroke with a progressively increased risk for systolic blood pressure within hypertension grade 1 (HR, 1.15 [95% CI, 1.06-1.24]), 2 (HR, 1.35 [95% CI, 1.25-1.47]), and 3 (HR, 1.63 [95% CI, 1.49-1.77]). 31786971 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE We used inverse variance weighting (IVW) to assess the relation of HbA1c with risk of hypertension (defined using the American College of Cardiology/American Heart Association 2017 guidelines), and SBP and DBP. 31386636 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE Epidemiological studies reported an inconsistent association between stage 1 hypertension (SBP 130-139 mmHg or DBP 80-89 mmHg) defined by the 2017 American College of Cardiology/American Heart Association hypertension guidelines and cardiovascular disease (CVD) events. 31790053 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE In fully adjusted models (including age, sex, BMI change during follow-up, baseline serum glucose, creatinine, total cholesterol office, home and 24-h SBP and DBP). higher LVMI values (i.e. the highest vs. the lowest quartile) were independently associated with an increased risk of home [odds ratio (OR) = 2.14, 95% confidence interval (CI) 1.21-3.77, P = 0.008] and 24-h ABP hypertension (OR = 1.70, 95% CI 1.05-2.76, P = 0.03). 31790069 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Despite similar baseline-BP in masked-HYP and normotensive individuals, during exercise masked-HYP exhibited a markedly greater (P < 0.01) SBP and DBP vs. normotensive individuals, and similar BP to true-HYP. 30817451 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Using the mean of the last two of three blood pressure (BP) measurements and questionnaire data, we defined hypertension as SBP at least 140 mmHg or DBP at least 90 mmHg or clinician-diagnosed hypertension. 30801386 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Moreover, increased blood Se concentrations were associated with body mass index (BMI) [odds ratio (OR): 2.56; 95% CI, 1.11, 5.93], high blood pressure [for both systolic and diastolic blood pressures (SBP and DBP); OR: 3.82; 95% CI, 1.47, 7.31 for SBP and OR: 2.56; 95% CI, 1.18, 5.59 for DBP], and hypertriglyceridemia (OR: 3.3; 95% CI, 1.51, 7.2). 30771749 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE The estimation errors of the model met the Association for the Advancement of Medical Instrumentation (AAMI) criteria (the SBP error was 2.5909 ± 3.4148 mmHg, and the DBP error was 2.6890 ± 3.3117 mmHg) and the Grade A British Hypertension Society criteria. 31847474 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Incident hypertension has been defined as the increase of SBP values over 140 mmHg and/or of DBP over 90 mmHg and or the beginning of an antihypertensive treatment. 30817453 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Achievement of target SBP without attention to decrease in DBP can increase cardiovascular morbidity in treated arterial hypertension: the Campania Salute Network. 31205199 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE Most markers of dyslipidemia (TG, HDL-C, LDL-C) and hypertension (SBP, DBP) were not associated (p > 0.05) with any total body or regional bone outcomes with the exception of the inverse relationship of LDL-C with total and trabecular BA and the positive relationship of DBP with cortical vBMD at the radius. 30572143 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE To evaluate the impact of the new US hypertension criteria [systolic blood pressure/diastolic blood pressure (SBP/DBP ≥130/80 mmHg)] on hypertension prevalence and the constituent ratio of three hypertension phenotypes. 30585785 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE Using data for 2,180 self-identified White, Black, Chinese, Japanese, and Hispanic participants from the Study of Women's Health Across the Nation, we examined associations among exposure to (higher vs. lower) everyday discrimination at baseline and BP and hypertension (HTN; systolic blood pressure [SBP] ≥ 140 mmHg; diastolic blood pressure [DBP] ≥ 90 mmHg; or self-reported HTN medication use) risk over a 10 year period. 30247506 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 AlteredExpression group BEFREE Despite the high prevalence of hypertension during the past 5 years, blood pressure levels increased significantly, especially the DBP level. 30882603 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE Newly defined stage 1 hypertension and elevated BP were associated with increased risk of incident CVD, whereas long-term changes of SBP and DBP had effects of varying degree on CVD incidence. 31116159 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE <b>Abbreviations:</b> AAP: American Academy of Pediatrics; BMI: body mass index; BP: blood pressure; cm: centimeter; DBP: diastolic blood pressure; HT: hypertension; kg: kilograms; m: meter; NHANES: National Health and Nutrition Examination Survey; ROC: receiver operating characteristic curve; SBP: systolic blood pressure; SBPHR: systolic blood pressure-to-height ratio; SD: standard deviation; WC: waist circumference; WHR: waist-to-height ratio. 31038015 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE In conclusion, the present study has identified Dbp, Crot and Mrpl4 as potential targets for the treatment of hypertension and stroke. 31545431 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Three separate types of control rates were calculated: SBP, DBP, and (combined) S&DBP among all participants with hypertension and participants with treated hypertension, separately. 31190479 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE Degree of hypertension had a direct relationship with NLR; SBP had a p value of 0.001 while the DBP had p = 0.002. 30835575 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE The results of subgroups showed that, there were statistically significant differences in the age of >50 years subgroup on ΔSBP [WMD = -2.32, 95% CI (-4.39, -0.25) P = .03]; there were statistically significant differences in the hypertension subgroup on ΔSBP [WMD = -6.58, 95% CI (-8.72, -4.44) P <.00001]; there were statistically significant differences in the hypertension subgroup on ΔDBP [WMD = -3.07, 95% CI (-4.66, -1.48) P = .0002]; there were statistically significant differences in the body mass index (BMI) >30 subgroup on ΔSBP [WMD = -3.51, 95% CI (-5.96, -1.07) P = .005]. 31083159 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 GeneticVariation group BEFREE After stratifying the subjects according to blood pressure and blood glucose, the positive relationship between RHR and UACR remained in the subjects with normal blood pressure and normal glucose tolerance, while in the hypertension (SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg) group and the diabetic mellitus (FPG ≥ 7.0 mmol/L and/or PPG ≥ 11.1 mmol/L) group, the relationship disappeared. 31534974 2019
Entrez Id: 1628
Gene Symbol: DBP
DBP
0.100 Biomarker group BEFREE In hypertension subgroup, buddhist activities related to SB is associated with a decrease in BP during linear regression analysis (standard β = -0.355; P = 0.004 for SBP; standard β = -0.345; P = 0.013 for DBP). 30420645 2019