Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Therapeutic phenotype RGD In "prevention" therapy, BH<sub>4</sub> (10 and 100 mg/kg) attenuated the development of PH in rat MCT model. eNOS protein levels in lung homogenates were maintained and cGMP levels were increased. 29151278 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype CTD_human We studied the correlation between the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and pulmonary hypertension in children with congenital cardiac diseases. 21144100 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype RGD Epigenetic regulation of the endothelial nitric oxide synthase gene in persistent pulmonary hypertension of the newborn rat. 20724942 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype RGD L-arginine may act through three pathways, providing a substrate for NO generation, preserving eNOS expression/phosphorylation, and maintaining the association of eNOS and HSP90, which allows restoration of eNOS activity and coupling activity, to maintain the balance between NO and O(2)(*-) and delay the development of PH. 20215577 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype RGD Sleeping Beauty-mediated eNOS gene therapy attenuates monocrotaline-induced pulmonary hypertension in rats. 17065228 2006