Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2152
Gene Symbol: F3
F3
0.020 Biomarker disease BEFREE The value of routine measurement of partial thromboplastin time or circulating D-dimer in patients with hyperthyroid or in patients treated with thyrotropin-suppressing dosage of T<sub>4</sub> requires clinical testing. 29742907 2018
Entrez Id: 2152
Gene Symbol: F3
F3
0.020 AlteredExpression disease BEFREE Patients with hyperthyroidism showed higher levels of fibrinogen (median (interquartile range), 315 (280-344) vs 262 (223-300), <i>P</i> = 0.001), D-dimer (103.8 (64.8-151.5) vs 50.7 (37.4-76.0), <i>P</i> < 0.001), peak thrombin (131.9 (102.2-159.4) vs 31.6 (14.8-83.7), <i>P</i> < 0.001) and endogenous thrombin potential (649 (538-736) vs 367 (197-1147), <i>P</i> = 0.021) in TGA with 1 pM tissue factor, neutrophil elastase (1.10 (0.39-2.18) vs 0.23 (0.20-0.35), <i>P</i> < 0.001), factor XIIa (66.9 (52.8-87.0) vs 73.0 (57.1-86.6), <i>P</i> < 0.001), HMWK (6.11 (4.95-7.98) vs 3.83 (2.60-5.68), <i>P</i> < 0.001), prekallikrein (2.15 (1.00-6.36) vs 1.41 (0.63-2.22), <i>P</i> = 0.026) and bradykinin (152.4 (137.6-180.4) vs 118.3 (97.1-137.9), <i>P</i> < 0.001) than did normal controls. 28137735 2017