Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human On the other hand, a dose of 10 micrograms of beta-endorphin(1-27), which lacks the four C-terminal amino acid residues of beta-endorphin, induced a fall in blood pressure and had a biphasic effect on heart rate. 1676337 1991
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human Use of antisera specifically recognizing the C-terminus of beta-, alpha-, and gamma-endorphin, respectively, revealed that only the beta-endorphin antiserum inhibited the fall in blood pressure in spontaneously hypertensive rats after cumulative administration of clonidine. 2536002 1989
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human Activation of brainstem endorphinergic neurons causes cardiovascular depression and facilitates baroreflex bradycardia. 2636709 1989
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.300 Biomarker phenotype CTD_human The results favor a role for beta-endorphin(1-31) and dynorphin(1-13) in the hypotension centrally mediated by alpha-methyldopa. 2566129 1989