Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 Biomarker disease BEFREE Antibodies to TSHR and IGF-1R were present in animals challenged with hTSHR A-subunit plasmid, with predominantly TSH blocking antibodies and were profoundly hypothyroid. 23900776 2013
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 Biomarker disease RGD Serum IGF-I levels were reduced by approximately 30% in all the 18-day-old hypothyroid animals, and did not correlate with the duration of the hypothyroid state. 1380443 1992
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 Biomarker disease BEFREE During follow-up he manifested complications from the hydrocephalus and NDI including global developmental delay and growth failure with low IGF-1 and hypothyroidism. 18553546 2008
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 GeneticVariation disease BEFREE These findings suggests that IGF-I (CA)(19) and IGFBP-3-202 A/C gene polymorphisms may be a risk factor for hypothyroidism. 19064126 2009
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 AlteredExpression disease BEFREE The most common endocrine abnormality was hypogonadism in 68%, followed by hyperprolactinemia (56%), hypothyroidism (54%), abnormal glucose metabolism (24%), adrenal insufficiency (17%), and high IGF-1 levels (15%). 30239770 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 GeneticVariation disease BEFREE Subsequent growth faltering is thought to be related to impairment of the GH/IGF-1 axis but children with T1DM are also more at risk of hypothyroidism and coeliac disease. 12373017 2002
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 Biomarker disease BEFREE A positive correlation between insulin and IGF-I and a poor correlation between GH and IGF-I were found in both hypothyroid neonates (T and MMI-hypothyroid). 9832414 1998
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.270 Biomarker disease BEFREE Population specific data and influence of sub-clinical hypothyroidism on insulin like growth factor-1 (IGF-1) and its binding protein-3 (IGFBP-3) in Indian children is lacking. 28672739 2017