Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker group BEFREE These peptides were applied to deliver ODNs against tumor necrosis factor-α (TNF-α) because TNF-α is a pro-inflammatory cytokine which plays an important role in immunological diseases. 30639220 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker group BEFREE Impaired TNF-α production as a marker of sepsis-associated innate immune dysfunction may be a feasible target for immune stimulation to decrease time to organ failure recovery. 28372498 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.100 Biomarker group BEFREE Understanding Foxp3 protein features and modulation mechanisms may help in the design of rational therapies for immune diseases and cancer. 31681337 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.100 AlteredExpression group BEFREE The results indicate that CDK8/19 is physiologically repressing Foxp3 expression in activated conventional T cells and that its pharmacological inhibition enables conversion of antigen-specific effector/memory T cells into Foxp3<sup>+</sup> T<sub>reg</sub> cells for the treatment of various immunological diseases. 31653719 2019
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.100 Biomarker group BEFREE Forkhead box P3 (Foxp3) regulates the immune response and plays an important role in immunological diseases. 30125971 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker group BEFREE Soluble TNFα Signaling within the Spinal Cord Contributes to the Development of Autonomic Dysreflexia and Ensuing Vascular and Immune Dysfunction after Spinal Cord Injury. 29610439 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 GeneticVariation group BEFREE To assess for a potential relationship between HSTCL and the use of TNF-α inhibitors, we searched for patients with HSTCL and underlying immune disorders at our institution. 28038706 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 GeneticVariation group BEFREE Polymorphisms of the heat shock protein 70-2 gene (HSP70-2) and the tumor necrosis factor-a gene (TNF-α) are known to be associated with immune diseases. 26547206 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker group BEFREE Psoriasis is a T cell-mediated immune disease in which various cytokines, primarily tumor necrosis factor-α (TNF-α), are complexly involved. 23113841 2014
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.100 AlteredExpression group BEFREE In contrast, inhibition of miR-210 increases FOXP3 expression and reverses the immune dysfunction in CD4(+) T cells from patients with PV. 24316592 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker group BEFREE Biologics to TNF family receptors are prime candidates for therapy of immune disease. 24958847 2014
Entrez Id: 7332
Gene Symbol: UBE2L3
UBE2L3
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 3428
Gene Symbol: IFI16
IFI16
0.100 GeneticVariation group GWASCAT Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
0.100 GeneticVariation group GWASCAT Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker group BEFREE The elevated erythrocyte sedimentation rate (ESR), IgG, neopterin, and TNF-α found in these patients suggested an immune disorder. 21402907 2011
Entrez Id: 919
Gene Symbol: CD247
CD247
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
0.100 GeneticVariation group GWASCAT Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 84162
Gene Symbol: KIAA1109
KIAA1109
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 100271700
Gene Symbol: NONOP2
NONOP2
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 105376550
Gene Symbol: LINC02752
LINC02752
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 26147
Gene Symbol: PHF19
PHF19
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 200734
Gene Symbol: SPRED2
SPRED2
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011
Entrez Id: 3560
Gene Symbol: IL2RB
IL2RB
0.100 GeneticVariation group GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967 2011