Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.330 AlteredExpression phenotype BEFREE In conclusion, up to the present time, captopril does not appear to induce a striking change in semen quality, and hence on male infertility, while it may affect the rate of spermatozoa-egg fusion as it inhibits the activity of angiotensin-converting enzyme that is released during capacitation and the acrosome reaction. 27444248 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.330 GeneticVariation phenotype BEFREE Thus, these ACE gene polymorphisms are unlikely to contribute to the pathogenesis of male infertility in the Singapore Chinese population. 11870238 2002
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.330 Biomarker phenotype BEFREE The ACE gene knockout mice lack both isozymes and they exhibit low blood pressure, kidney dysfunctions, and male infertility. 9664078 1998
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.330 Biomarker phenotype CTD_human Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. 8642790 1996