| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.550 | Biomarker | phenotype | RGD | Although overexpression of renal Smad7 had no effect on levels of blood glucose, it significantly attenuated the development of microalbuminuria, TGF-β/Smad3-mediated renal fibrosis such as collagen I and IV and fibronectin accumulation and NF-κB/p65-driven renal inflammation including IL-1β, TNF-α, MCP-1, and ICAM-1 expression and macrophage infiltration in diabetic rats. | 20980457 | 2011 | ||||
|
0.550 | AlteredExpression | phenotype | LHGDN | In CAPD patients, carotid atherosclerosis is associated with markers of inflammation, malnutrition and circulating levels of adhesion molecule ICAM-1. | 14993495 | 2004 | ||||
|
0.550 | Biomarker | phenotype | CTD_human | Anti-inflammatory and antioxidant effects of SERPINA3K in the retina. | 19324842 | 2009 | ||||
|
0.550 | Biomarker | phenotype | LHGDN | Increased soluble intercellular adhesion molecule-1, breast cancer and the acute phase response. | 11914659 | 2002 | ||||
|
0.550 | AlteredExpression | phenotype | LHGDN | 1,25(OH)2D3 and EB 1089 inhibit PBMC proliferation, induce apoptosis in PBMC of healthy subjects and IBD patients, and affect ICAM-1 expression on PBMC and on HUVEC cocultured with PBMC, suggesting that the ICAM-1 downregulation could provide a new target for controlling the recruitment of leukocytes at the sites of inflammation in IBD. | 18200516 | 2008 | ||||
|
0.550 | Biomarker | phenotype | CTD_human | Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats. | 23371441 | 2013 | ||||
|
0.550 | Biomarker | phenotype | LHGDN | An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. | 17116732 | 2006 | ||||
|
0.550 | Biomarker | phenotype | LHGDN | Our finding of increased concentrations of ICAM-1 in SLE patients with nephritis underlines the importance of inflammation and endothelial involvement in this disease, but their predictive value in the disease monitoring need to be further studied. | 17340048 | 2007 |