| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.340 | Biomarker | phenotype | CTD_human | Emodin-6-O-β-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo. | 23146691 | 2013 | ||||
|
0.340 | Biomarker | phenotype | CTD_human | Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses. | 22178603 | 2012 | ||||
|
0.340 | Biomarker | phenotype | CTD_human | Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models. | 22429818 | 2012 | ||||
|
0.340 | Biomarker | phenotype | CTD_human | Further, high plasma levels of HMGB1 correlate with poor prognosis and increased mortality in patients with severe inflammation. | 22386814 | 2012 | ||||
|
0.340 | Biomarker | phenotype | CTD_human | Peroxisome proliferator-activated receptor γ agonist troglitazone inhibits high mobility group box 1 expression in endothelial cells via suppressing transcriptional activity of nuclear factor κB and activator protein 1. | 21617575 | 2011 | ||||
|
0.340 | Biomarker | phenotype | LHGDN | The current study has revealed that HMGB-1 is elevated significantly in CKD patients and correlates with GFR as well as markers of inflammation and malnutrition. | 18317568 | 2008 | ||||
|
0.340 | Biomarker | phenotype | LHGDN | Dengue virus infection induces passive release of high mobility group box 1 protein by epithelial cells. | 18076993 | 2008 | ||||
|
0.340 | Biomarker | phenotype | LHGDN | HMGB1 can be released in the vitreous of eyes with endophthalmitis depending on inflammation and tissue damage. | 18431589 | 2008 | ||||
|
0.340 | Biomarker | phenotype | LHGDN | In apoptotic cells, HMGB1 is bound firmly to chromatin because of generalized underacetylation of histone and is released in the extracellular medium (promoting inflammation) if chromatin deacetylation is prevented. | 12110890 | 2002 |