| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.350 | Biomarker | phenotype | CTD_human | Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and stromal cells of the bovine endometrium. | 22053092 | 2012 | ||||
|
0.350 | Biomarker | phenotype | CTD_human | Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses. | 22178603 | 2012 | ||||
|
0.350 | Biomarker | phenotype | CTD_human | The observation that these responses to ozone were not evident in TLR4 mutant C3H/HeJ mice demonstrates that functional TLR4 contributes to ozone-induced sterile inflammation and macrophage activation. | 22300504 | 2012 | ||||
|
0.350 | Biomarker | phenotype | LHGDN | These results suggest that TLR2 and TLR4 may play a role in aortic valve inflammation and stenosis. | 17942642 | 2008 | ||||
|
0.350 | Biomarker | phenotype | LHGDN | These observations support the notion of a potential role for activation through TLR-2 and TLR-4 in the inflammation and joint destruction of RA. | 17599732 | 2007 | ||||
|
0.350 | Biomarker | phenotype | CTD_human | Here we report that toll-like receptor 4 (TLR4) may mediate the ganglioside-triggered inflammation in glia, brain resident immune cells. | 16651628 | 2006 | ||||
|
0.350 | AlteredExpression | phenotype | LHGDN | These findings suggest that NADPH oxidase activation, mRNA stabilization, and MAPK signaling pathways play critical roles in LPS-enhanced TLR4 expression in HASMCs, which contributes to vascular inflammation and cardiovascular disorders. | 17008589 | 2006 | ||||
|
0.350 | AlteredExpression | phenotype | LHGDN | Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis. | 16146574 | 2005 | ||||
|
0.350 | Biomarker | phenotype | LHGDN | TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression. | 17057796 | 2005 |