Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Therapeutic phenotype RGD The results showed that intraplantar injection of carrageenan led to time-dependent development of peripheral inflammation, which resulted in a significant increase in the levels of tumor necrosis factor α (TNF-α) and interleukin 1 (IL-1) β, nitric oxide (NO) and prostaglandin E2 (PGE2) and also iNOS and COX-2 protein expression in inflamed paw. 26069367 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Therapeutic phenotype RGD The galactose-binding lectin isolated from Bauhinia bauhinioides Mart seeds inhibits neutrophil rolling and adhesion via primary cytokines. 25706245 2015
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats. 23371441 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Citronellal, a monoterpene present in Java citronella oil, attenuates mechanical nociception response in mice. 23795810 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Anti-inflammatory activity of patchouli alcohol in RAW264.7 and HT-29 cells. 23348408 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Quercetin attenuates TNF-induced inflammation in hepatic cells by inhibiting the NF-κB pathway. 22452660 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats. 21467745 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human UDCA-LPE inhibited TNFα-induced apoptosis and inflammation in hepatocytes in vitro and markedly ameliorated GalN/LPS-mediated fulminant hepatitis in mice, whereas UDCA or PC failed to show protection. 21146893 2011
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype CTD_human Association of ankle-arm index with inflammation and mineral bone disorder in hemodialysis patients. 21437516 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human The aim of this study was to examine the extent to which quercetin and trans-RSV prevented inflammation or insulin resistance in primary cultures of human adipocytes treated with tumor necrosis factor-α (TNF-α)-an inflammatory cytokine elevated in the plasma and adipose tissue of obese, diabetic individuals. 20943792 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice. 19803787 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Niacin also inhibited intima-media neutrophil recruitment and myeloperoxidase accumulation, enhanced endothelial-dependent vasorelaxation and cyclic guanosine monophosphate production, increased vascular reduced glutathione content, and protected against hypochlorous acid-induced endothelial dysfunction and tumor necrosis factor alpha-induced vascular inflammation. 20167660 2010
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype RGD The effects of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha in rat allograft adventitial inflammation and allograft arteriosclerosis. 19917410 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype CTD_human Anti-inflammatory and antioxidant effects of SERPINA3K in the retina. 19324842 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype LHGDN The role of water channel aquaporin 3 in the mechanism of TNF-alpha-mediated proinflammatory events: Implication in periodontal inflammation. 18543247 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN C-reactive protein and coronary calcium score association in coronary artery disease. 18810717 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN Impact of metabolic syndrome on the long-term survival of patients with acute myocardial infarction: potential association with C-reactive protein. 18296838 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN Procalcitonin fails to differentiate inflammatory status or predict long-term outcomes in peritoneal dialysis-associated peritonitis. 18556380 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are common measures of systemic inflammation. 18078625 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN Similar to C-reactive protein (CRP), it may be another marker of systemic inflammation. 18605934 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN Association between markers of renal function and C-reactive protein level in the elderly: confounding by functional status. 18609082 2008
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 AlteredExpression phenotype LHGDN Proinflammatory cytokines seem to be only partly involved in the pathophysiology of CRPS1, as indicated by the lack of coherence between TNF-alpha and IL-6 levels and the signs and symptoms of inflammation and disease duration. 18055234 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN High-sensitivity C-reactive protein is independently associated with early carotid artery progression in women but not in men: the INVADE Study. 17885262 2007
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker phenotype LHGDN CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. 17660390 2007
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.600 Biomarker phenotype LHGDN Serum amyloid P and cardiovascular disease in older men and women: results from the Cardiovascular Health Study. 17138933 2007