Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 GeneticVariation group GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 Biomarker group BEFREE Our results supporting IL2RA and IL2RB as promising candidate genes for IBD and suggesting a potential role of IL2R in the pathogenesis of IBD, likely involves regulatory T cells. 23972291 2013
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 GeneticVariation group GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 GeneticVariation group GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 AlteredExpression group BEFREE The downregulation of TRF2 and RAP1 mRNA expression in CD25+ T-lymphocytes in IBD suggests that these telomere binding proteins play a role in telomere regulation and may contribute to the telomeric fusions and chromosomal abnormalities observed in UC. 20061197 2010
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 Biomarker group BEFREE Therefore, we decide to investigate the association of polymorphisms in the IL-2 axis (IL2, IL2RA, and IL2RB genes) with inflammatory bowel diseases (IBDs). 19471255 2009
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 Biomarker group BEFREE Intestinal homeostasis and maintenance of tolerance to harmless antigens in the intestine has been shown to be maintained by CD4+ CD25+ T regulatory cells (Treg) in animal models of inflammatory bowel diseases. 18422560 2008
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 AlteredExpression group BEFREE Interestingly, LP CD4(+)CD25(bright) T cells with regulatory T activity were significantly increased in patients with active inflammatory bowel disease. 15322172 2004
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.350 Biomarker group MGD