Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 AlteredExpression disease BEFREE When these gradient fractions were treated with 0.01% trypsin for 30 min, the Nagalase activity of each fraction increased significantly, suggesting that the Nagalase activity resides on an outer envelope protein of the influenza virion and is enhanced by the proteolytic process. 15848273 2005
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors. 16397505 2006
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE The hemagglutinin (HA) envelope protein of influenza viruses mediates essential viral functions, including receptor binding and membrane fusion, and is the major viral antigen for antibody neutralization. 20007271 2010
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE Influenza virus hemagglutinin (HA) is the viral envelope protein that mediates viral attachment to host cells and elicits membrane fusion. 22072785 2012
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE Influenza vaccines must be frequently reformulated to account for antigenic changes in the viral envelope protein, hemagglutinin (HA). 26739054 2016
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE The viral envelope protein hemagglutinin (HA) plays a critical role in influenza entry and thus is an attractive target for novel therapeutics. 27759373 2016
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE Hemagglutinin (HA)is an important envelope protein for the entry of influenza viruses into host cells, thus, HA-targeted agents may be potential anti-influenza drugs. 27918208 2017
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE The fusion peptides are derived from the influenza virus hemagglutinin fusion protein (HA2-FP) and from the tick-borne encephalitis virus envelope glycoprotein E (TBEV-FP). 28829131 2017
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 GeneticVariation disease BEFREE The hu-mAbs were designed for targeting a human B-cell epitope (<sup>180</sup>WGIHHPPNSKEQ QNLY<sup>195</sup>) of hemagglutinin (HA) envelope protein of PR8/A/34 (H1N1) virus with high homology among seven influenza type A viruses. 29135340 2018
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE Influenza hemagglutinin (HA) is the canonical type I viral envelope glycoprotein and provides a template for the membrane-fusion mechanisms of numerous viruses. 29961575 2018
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.100 Biomarker disease BEFREE Targeting of antigens to the dendritic cell (DC) molecule Clec9A has been shown to enhance antibody affinity and titers for model antigens, and influenza and enterovirus antigens, and may be advantageous for immunogens that otherwise fail to elicit antibodies with sufficient titers and breadth for broad protection, such as the envelope protein (Env) of HIV. 31430333 2019