Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Transcriptome Profiling Reveals Differential Effect of Interleukin-17A Upon Influenza Virus Infection in Human Cells. 31681209 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Although there is increasing evidence that IL-17 is involved in protective immunity against H1 and H3 influenza virus infections, little is known about the role of IL-17 in the highly pathogenic H5N1 influenza virus infection. 21946434 2011
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Moreover, antibiotic depletion of intestinal microbiota reduced IL-17A production and attenuated influenza-caused intestinal injury. 25366965 2014
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 AlteredExpression disease BEFREE Lactobacilli treated mice also showed reduced concentrations of IL-17 and improved levels of IL-10 during IFV infection. 31841753 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE By conducting the MCCV on seed cross-talk, 3 hub cross-talk for BPD were uncovered: i) The pair of pathways role of interleukin-17F (IL-17F) in allergic inflammatory airway diseases and role of IL-17A in psoriasis; ii) the pair of pathways role of IL random forest 17A in psoriasis and IL-17A signaling in fibroblasts and ii) the pair of pathways IL-17A signaling in airway cells and role of hypercytokinemia/hyperchemokinemia in the pathogenesis of influenza. 30930971 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Neonates lacking IL-17A-expressing γδ T cells or Il33 had higher mortality upon influenza infection. 30170813 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Because IL-17A and IL-17F, ligands for IL-17 receptor antagonist (IL-17RA), have been shown to mediate neutrophil migration into the lung in response to LPS or Gram-negative bacterial pneumonia, we hypothesized that IL-17RA signaling was critical for acute lung injury in response to pulmonary influenza infection. 19783685 2009
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Our data show that although IL-17A reduces S. pneumoniae colonization, coinfection with influenza virus elicits a robust innate IL-17A response that promotes inflammation and S. pneumoniae disease in the nasopharynx. 31185076 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE The importance of our research is in determining that influenza and its component haemagglutinin has a direct effect on the classic pneumococcus induced pathways to IL-17A in our human ex vivo model. 30192848 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 GeneticVariation disease BEFREE The frequencies of the IL-1β rs16944 (P = 0.007) and IL-17 rs2275913 (P = 0.006) genotypes were associated with severe influenza disease, while the frequencies of IL-10 rs1800872 and IL-28 rs8099917 were not associated with the disease (P > 0.05). 31196204 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Furthermore, we show that exogenous IL-1β can drastically alter Th1 responses driven by influenza and lymphocytic choriomeningitis virus infection models and induce IL-17 production. 27328989 2017
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Early production of IL-17A by γδ T cells in the trachea promotes viral clearance during influenza infection in mice. 31777067 2020