Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD
0.260 Biomarker disease BEFREE Since SP-D affinity for influenza HA depends on the presence of high mannose glycan on the head region our data demonstrate that SP-D may not protect against virus containing these HA subtypes. 31826991 2020
Entrez Id: 116442
Gene Symbol: RAB39B
RAB39B
0.100 Biomarker disease BEFREE In this study, we have examined the ability of a novel sulfonated derivative of β-cyclodextrin (KS-6469) to inhibit the influenza virus A/WSN/33 (H1N1) infection in vitro and in vivo. 31720013 2020
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.100 Biomarker disease BEFREE The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I. 31843969 2020
Entrez Id: 10625
Gene Symbol: IVNS1ABP
IVNS1ABP
0.100 Biomarker disease BEFREE The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I. 31843969 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 AlteredExpression disease BEFREE Lactobacilli treated mice also showed reduced concentrations of IL-17 and improved levels of IL-10 during IFV infection. 31841753 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.100 AlteredExpression disease BEFREE The mechanisms exploration revealed that MENK (10 mg/mL) significantly inhibited the nucleoprotein (NP) of influenza virus and up-regulated levels of IL-6, TNF-α and IFN-β compared with those in H1N1 control group. 31835089 2020
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.100 Biomarker disease BEFREE SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection. 31782850 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 AlteredExpression disease BEFREE Lactobacilli treated mice also showed reduced concentrations of IL-17 and improved levels of IL-10 during IFV infection. 31841753 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.100 Biomarker disease BEFREE Early production of IL-17A by γδ T cells in the trachea promotes viral clearance during influenza infection in mice. 31777067 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 Biomarker disease BEFREE Moreover, PSF efficiently decreased the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-4, interferon (IFN)-γ, thromboxane A<sub>2</sub> (TXA<sub>2</sub>), and prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) in lung tissues of mice infected with influenza virus (p < 0.05-0.01). 31446589 2020
Entrez Id: 391104
Gene Symbol: VHLL
VHLL
0.070 Biomarker disease BEFREE Our results indicate the potential of the VLP vaccine approach in terms of immunogenicity but suggest that anti-HA immunity should not be considered as the sole preventive method for combatting influenza and postinfluenza bacterial infections. 31718898 2020
Entrez Id: 54504
Gene Symbol: CPVL
CPVL
0.070 Biomarker disease BEFREE Our results indicate the potential of the VLP vaccine approach in terms of immunogenicity but suggest that anti-HA immunity should not be considered as the sole preventive method for combatting influenza and postinfluenza bacterial infections. 31718898 2020
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.060 Biomarker disease BEFREE Moreover, PSF efficiently decreased the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-4, interferon (IFN)-γ, thromboxane A<sub>2</sub> (TXA<sub>2</sub>), and prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) in lung tissues of mice infected with influenza virus (p < 0.05-0.01). 31446589 2020
Entrez Id: 50616
Gene Symbol: IL22
IL22
0.060 Biomarker disease BEFREE Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection. 31597930 2020
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.040 Biomarker disease BEFREE In Denmark, the diphtheria, tetanus, pertussis, polio and Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine is recommended at ages 3, 5 and 12 months and the first measles-mumps-rubella vaccine (MMR-1) at 15 months. 30024308 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.040 Biomarker disease BEFREE Antitumor efficacy of <sup>212</sup>Pb-L2 was evaluated in PSMA(+) PC3 PIP and PSMA(-) PC3 flu tumor models and in the PSMA(+) luciferase-expressing micrometastatic model. 31253744 2020
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
0.040 Biomarker disease BEFREE Prion Protein is a Novel Modulator of Influenza: Potential Implications for Anti-Influenza Therapeutics. 31814573 2020
Entrez Id: 6395
Gene Symbol: SEA
SEA
0.020 Biomarker disease BEFREE Routine surveillance of avian influenza viruses should be continuously conducted to understand the dynamic and diversity of the viruses for influenza prevention and control in Indonesia and SEA region. 31770478 2020
Entrez Id: 8125
Gene Symbol: ANP32A
ANP32A
0.020 Biomarker disease BEFREE Elucidating the interactions between influenza virus polymerase and host factor ANP32A. 31694956 2020
Entrez Id: 7415
Gene Symbol: VCP
VCP
0.010 AlteredExpression disease BEFREE Furthermore, p97 activity has been shown to be essential for the replication of certain viruses, including poliovirus, herpes simplex virus (HSV), cytomegalovirus (CMV), and influenza. 31550150 2020
Entrez Id: 5708
Gene Symbol: PSMD2
PSMD2
0.010 AlteredExpression disease BEFREE Furthermore, p97 activity has been shown to be essential for the replication of certain viruses, including poliovirus, herpes simplex virus (HSV), cytomegalovirus (CMV), and influenza. 31550150 2020
Entrez Id: 10428
Gene Symbol: CFDP1
CFDP1
0.010 AlteredExpression disease BEFREE Furthermore, p97 activity has been shown to be essential for the replication of certain viruses, including poliovirus, herpes simplex virus (HSV), cytomegalovirus (CMV), and influenza. 31550150 2020
Entrez Id: 1982
Gene Symbol: EIF4G2
EIF4G2
0.010 AlteredExpression disease BEFREE Furthermore, p97 activity has been shown to be essential for the replication of certain viruses, including poliovirus, herpes simplex virus (HSV), cytomegalovirus (CMV), and influenza. 31550150 2020
Entrez Id: 50628
Gene Symbol: GEMIN4
GEMIN4
0.010 AlteredExpression disease BEFREE Furthermore, p97 activity has been shown to be essential for the replication of certain viruses, including poliovirus, herpes simplex virus (HSV), cytomegalovirus (CMV), and influenza. 31550150 2020
Entrez Id: 116379
Gene Symbol: IL22RA2
IL22RA2
0.010 Biomarker disease BEFREE Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection. 31597930 2020