| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Furthermore, 10 (27.0%) were b-lactamase-producing ampicillin-resistance (BLPAR) (TEM-1 type)strains, 11 (29.8%) were low-b-lactamase-nonproducing ampicillin-resistant H. influenzae (Low-BLNAR) strains,and the rest were b-lactamase-negative ampicillin-susceptible(BLNAS) strains. | 22302696 | 2012 | ||||
|
0.080 | Biomarker | disease | BEFREE | β-lactamase production was identified in 27.5 % of NTHi isolates (all TEM-1), while β-lactamase-negative ampicillin resistance and β-lactamase-negative amoxicillin-clavulanate resistance among NTHi was 16.9 and 6.4 %, respectively. | 22538797 | 2012 | ||||
|
0.080 | Biomarker | disease | BEFREE | Therefore, bla(TEM-1) β-lactamase is the main mechanism for resistance of H. influenzae to ampicillin in Chongqing. | 23009117 | 2012 | ||||
|
0.080 | Biomarker | disease | BEFREE | To study yearly changes in resistance and to identify ftsI mutations in beta-lactamase-non-producing ampicillin-resistant (BLNAR) and TEM-1 beta-lactamase-producing amoxicillin/clavulanic acid-resistant (BLPACR) isolates of Haemophilus influenzae from patients with meningitis. | 16617062 | 2006 | ||||
|
0.080 | Biomarker | disease | BEFREE | Global distribution of TEM-1 and ROB-1 beta-lactamases in Haemophilus influenzae. | 16096320 | 2005 | ||||
|
0.080 | Biomarker | disease | BEFREE | We surveyed 161 clinical isolates of ampicillin-resistant, beta-lactamase-producing isolates of Haemophilus influenzae obtained between 1975 and 1985 to determine whether they produced TEM-1 or Rob beta-lactamase. | 3257784 | 1988 | ||||
|
0.080 | Biomarker | disease | BEFREE | The most common cause of ampicillin resistance in Haemophilus influenzae type b is production of TEM-1 beta-lactamase; however, a novel enzyme with a similar substrate profile but a quite different isoelectric point has also been described. | 3487284 | 1986 | ||||
|
0.080 | Biomarker | disease | BEFREE | Documented ampicillin treatment failures of systemic Haemophilus influenzae type b infections have been associated with synthesis of a TEM-1 beta-lactamase. | 6118476 | 1981 |