Gene: TLR2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease BEFREE TLR2-deficient mice exacerbated renal injury in cisplatin-induced AKI, with higher serum creatinine and blood urea nitrogen, more severe morphological injury compared with that of wild-type mice. 30387162 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease BEFREE For the present study, it was hypothesized that TLR2 inhibition could reduce inflammation and consequently prevent septic AKI. 31798708 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease BEFREE Adoptive transfer of TLR-2-primed WTDCs significantly expanded Tregs in the kidneys of CDDP-treated WT and Gal-3<sup>-/-</sup> recipients resulting in the suppression of IFN-γ and IL-17-driven inflammation and alleviation of AKI. 31534532 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease CTD_human Relevance of megalin receptor injury with nuclear factor-kappa B upregulation in acute kidney injury induced in rats. 29286200 2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease BEFREE Hence, the present study aimed to evaluate the specific participation of TLR2 and TLR4 molecules on the development of cisplatin-induced AKI. 29500224 2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease BEFREE We propose that the TLR1/TLR2 heterodimer may be a new therapeutic target for the prevention of acute kidney injury in diabetic patients. 28822965 2017
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.360 Biomarker disease BEFREE Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury. 24480070 2014