×
Entrez Id:
1201
Gene Symbol:
CLN3
CLN3
0.500
Biomarker
disease
CTD_human
×
Entrez Id:
2055
Gene Symbol:
CLN8
CLN8
0.200
Biomarker
disease
MGD
Mapping of the motor neuron degeneration (Mnd) gene, a mouse model of amyotrophic lateral sclerosis (ALS).
1639406
1992
×
Entrez Id:
2055
Gene Symbol:
CLN8
CLN8
0.200
Biomarker
disease
MGD
Autosomal dominance in a late-onset motor neuron disease in the mouse.
3783318
1986
×
Entrez Id:
1509
Gene Symbol:
CTSD
CTSD
0.200
Biomarker
disease
MGD
Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells.
7641679
1995
×
Entrez Id:
2055
Gene Symbol:
CLN8
CLN8
0.200
Biomarker
disease
MGD
Motor neuron degeneration of mice is a model of neuronal ceroid lipofuscinosis (Batten's disease).
7683855
1993
×
Entrez Id:
2055
Gene Symbol:
CLN8
CLN8
0.200
Biomarker
disease
MGD
Retinal degeneration in motor neuron degeneration (mnd) mutant mice.
8282051
1993
×
Entrez Id:
1509
Gene Symbol:
CTSD
CTSD
0.200
Biomarker
disease
MGD
Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation.
9539769
1998
×
Entrez Id:
54982
Gene Symbol:
CLN6
CLN6
0.830
Biomarker
disease
MGD
Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9.
9600738
1998
×
Entrez Id:
2055
Gene Symbol:
CLN8
CLN8
0.200
Biomarker
disease
MGD
An early-onset congenic strain of the motor neuron degeneration (mnd) mouse.
10191135
1999
×
Entrez Id:
1200
Gene Symbol:
TPP1
TPP1
0.500
Biomarker
disease
CTD_human
Increased brain lysosomal pepstatin-insensitive proteinase activity in patients with neurodegenerative diseases.
10320038
1999
×
Entrez Id:
1201
Gene Symbol:
CLN3
CLN3
0.500
Biomarker
disease
MGD
A mouse gene knockout model for juvenile ceroid-lipofuscinosis (Batten disease).
10440905
1999
×
Entrez Id:
1201
Gene Symbol:
CLN3
CLN3
0.500
Biomarker
disease
MGD
Targeted disruption of the Cln3 gene provides a mouse model for Batten disease. The Batten Mouse Model Consortium [corrected].
10527801
1999
×
Entrez Id:
1509
Gene Symbol:
CTSD
CTSD
0.200
Biomarker
disease
MGD
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons.
10995834
2000
×
Entrez Id:
1509
Gene Symbol:
CTSD
CTSD
0.200
Biomarker
disease
MGD
Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice.
11567042
2001
×
Entrez Id:
1200
Gene Symbol:
TPP1
TPP1
0.500
Biomarker
disease
CTD_human
Aminoglycoside-mediated suppression of nonsense mutations in late infantile neuronal ceroid lipofuscinosis.
11589009
2001
×
Entrez Id:
5538
Gene Symbol:
PPT1
PPT1
0.200
Biomarker
disease
MGD
Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice.
11717424
2001
×
Entrez Id:
1182
Gene Symbol:
CLCN3
CLCN3
0.200
Biomarker
disease
MGD
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis.
12059962
2002
×
Entrez Id:
1201
Gene Symbol:
CLN3
CLN3
0.500
Biomarker
disease
MGD
Cln3(Deltaex7/8) knock-in mice with the common JNCL mutation exhibit progressive neurologic disease that begins before birth.
12374761
2002
×
Entrez Id:
1509
Gene Symbol:
CTSD
CTSD
0.200
Biomarker
disease
MGD
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice.
12676526
2003
×
Entrez Id:
4691
Gene Symbol:
NCL
NCL
0.010
GeneticVariation
disease
BEFREE
Autosomal dominant adult neuronal ceroid lipofuscinosis : a novel form of NCL with granular osmiophilic deposits without palmitoyl protein thioesterase 1 deficiency.
14655761
2003
×
Entrez Id:
1201
Gene Symbol:
CLN3
CLN3
0.500
Biomarker
disease
MGD
Altered gene expression in the eye of a mouse model for batten disease.
15326100
2004
×
Entrez Id:
1203
Gene Symbol:
CLN5
CLN5
0.200
Biomarker
disease
MGD
A mouse model for Finnish variant late infantile neuronal ceroid lipofuscinosis, CLN5, reveals neuropathology associated with early aging.
15459177
2004
×
Entrez Id:
1200
Gene Symbol:
TPP1
TPP1
0.500
Biomarker
disease
MGD
A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration.
15483130
2004
×
Entrez Id:
1182
Gene Symbol:
CLCN3
CLCN3
0.200
Biomarker
disease
MGD
ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.
15504734
2005
×
Entrez Id:
5538
Gene Symbol:
PPT1
PPT1
0.200
Biomarker
disease
MGD
Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons.
15649713
2005