Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.310 GeneticVariation disease BEFREE Endothelial nitric oxide synthase genotype is associated with pulmonary hypertension severity in left heart failure patients. 29718770 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.310 GeneticVariation disease BEFREE DNA samples from 118 patients with HF-PH were genotyped for the NOS3 rs1799983 and NOS2 rs3730017 polymorphisms. 29718770 2019
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2
0.310 Biomarker disease BEFREE Several large clinical studies have demonstrated the important benefit of mineralocorticoid receptor (MR) antagonists in patients with heart failure, left ventricular dysfunction after myocardial infarction, hypertension or diabetic nephropathy. 21784127 2012
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2
0.310 Biomarker disease CTD_human Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. 21321305 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.310 Biomarker disease CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.310 Biomarker disease CTD_human Isoproterenol-induced heart failure in the rat is associated with nitric oxide-dependent functional alterations of cardiac function. 19168511 2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.310 Biomarker disease CTD_human Isoproterenol-induced heart failure in the rat is associated with nitric oxide-dependent functional alterations of cardiac function. 19168511 2009
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2
0.310 Biomarker disease CTD_human Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure. 15722665 2005
Entrez Id: 35
Gene Symbol: ACADS
ACADS
0.300 Biomarker disease CTD_human [Change of short-chain acyl-CoA dehydrogenase in heart failure after myocardial infarction in rats and the intervention of aerobic exercise]. 30827304 2019
Entrez Id: 6659
Gene Symbol: SOX4
SOX4
0.300 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.300 Biomarker disease CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987 2018
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.300 Biomarker disease CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987 2018
Entrez Id: 9475
Gene Symbol: ROCK2
ROCK2
0.300 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 57057
Gene Symbol: TBX20
TBX20
0.300 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.300 Biomarker disease CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.300 Biomarker disease CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987 2018
Entrez Id: 9464
Gene Symbol: HAND2
HAND2
0.300 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.300 Biomarker disease CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987 2018
Entrez Id: 11034
Gene Symbol: DSTN
DSTN
0.300 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
0.300 Therapeutic disease CTD_human TLR2 and TLR3 expression as a biomarker for the risk of doxorubicin-induced heart failure. 29959987 2018
Entrez Id: 25805
Gene Symbol: BAMBI
BAMBI
0.300 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.300 Biomarker disease CTD_human Hypereosinophilic Syndrome as a Rare Cause of Reversible Biventricular Heart Failure. 28347583 2017
Entrez Id: 81608
Gene Symbol: FIP1L1
FIP1L1
0.300 Biomarker disease CTD_human Hypereosinophilic Syndrome as a Rare Cause of Reversible Biventricular Heart Failure. 28347583 2017
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.300 Therapeutic disease CTD_human Loss of Nrf2 promotes rapid progression to heart failure following myocardial infarction. 28373008 2017
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
0.300 Biomarker disease CTD_human Influence of Mechanical Circulatory Support on Endothelin Receptor Expression in Human Left Ventricular Myocardium from Patients with Dilated Cardiomyopathy (DCM). 28095452 2017