Gene: TLR4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.050 AlteredExpression disease BEFREE We also determined if there was an association of either the pro-inflammatory cytokine TNF or the anti-inflammatory cytokine IL-10 with TLR2 or TLR4 expression levels after <i>L. braziliensis</i> infection.<i>In vitro</i> infection with <i>L. braziliensis</i> caused CL monocytes to up-regulate TLR2 and TLR4 expression. 31119102 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.050 GeneticVariation disease BEFREE Screening of TNFα, IL-10 and TLR4 single nucleotide polymorphisms in individuals with asymptomatic and chronic cutaneous leishmaniasis in Colombia: a pilot study. 28241747 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.050 Biomarker disease BEFREE The data suggested a possible role for TLR2 and TLR4 in the outcome of CL lesion. 23980810 2013
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.050 GeneticVariation disease BEFREE TLR4 896 A>G increased risk for all parasitic infections (ORG 1.59; 95%CI 1.05-2.42), malaria (1.31; 95%CI 1.04-1.66), brucellosis (2.66; 95%CI 1.66-4.27), cutaneous leishmaniasis (7.22; 95%CI 1.91-27.29), neurocysticercosis (4.39; 95%CI 2.53-7.61), Streptococcus pyogenes tonsillar disease (2.93; 95%CI 1.24-6.93) , typhoid fever (2.51; 95%CI 1.18-5.34) and adult urinary tract infections (1.98; 95%CI 1.04-3.98), but was protective for leprosy (0.36; 95%CI 0.22-0.60). 24282567 2013
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.050 GeneticVariation disease BEFREE In the present study the associations between TLR4 mutations (Asp299Gly and Thr399Ile) with outcome of CL have been investigated. 21056683 2011