Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | GeneticVariation | disease | BEFREE | Alleles rs2276631-C (P = 0.02; OR [95%CI] = 2.11 [1.16-3.86]) and rs2279015-G (P = 0.005; OR [95%CI] = 2.42 [1.33-4.41]) of SLC11A1, were associated with susceptibility to VL, whereas genotypes rs2276631 C/C (P = 0.003; OR [95%CI] = 2.65 [1.41-5.00]) and rs2279015 G/G (P = 0.018; OR [95%CI] = 2.05 [1.15-3.64]) were significantly increased in CL and VL patients, respectively. | 25603101 | 2015 | ||||
|
0.370 | Biomarker | disease | CTD_human | Iron and infection: effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLC11A1) on host-pathogen interactions in tuberculosis and HIV. | 16597321 | 2006 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | No associations were observed between VL and polymorphisms at SLC11A1 that were either robust to correction for multiple testing or replicated across primary and replication samples. | 21599885 | 2011 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | Our results suggest that polymorphisms in SLC11A1 affect susceptibility to CL and VL. | 31230160 | 2019 | ||||
|
0.370 | GeneticVariation | disease | LHGDN | Studies have shown that the Nramp1 and H-2 genes are implicated in the control of Leishmania donovani infection in mice. | 12618857 | 2003 | ||||
|
0.370 | Biomarker | disease | BEFREE | Studies have shown that the Nramp1 and H-2 genes are implicated in the control of Leishmania donovani infection in mice. | 12618857 | 2003 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | Susceptibility to KA was shown to depend on a locus on chromosomes 22q12 and on NRAMP1 on chromosome 2q35; the data also suggested a third locus in the region 2q23-q24. | 17067929 | 2006 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | This study aimed to determine possible association of SLC11A1 polymorphisms with visceral leishmaniasis among Moroccan children. | 25151047 | 2014 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | We therefore examined polymorphisms at SLC11A1 in 59 multicase families of VL from the high-incidence Masalit tribe in Sudan. | 14523377 | 2004 |