Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.050 Biomarker disease BEFREE However, individuals with sVL had fewer regulatory cells after SLA stimulation (CD4<sup>+</sup> CD25<sup>HIGH</sup>, <i>P</i> = 0.04 and CD4<sup>+</sup> FOXP3+, <i>P</i> = 0.02) than RecVL. 29280433 2018
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.050 Biomarker disease BEFREE Moreover, the direct evidence of CD4+CD25+FoxP3+ Treg cells as a source of IL-10 and TGFβ during active VL could open new avenues for immunotherapy towards cure of this potentially fatal disease. 26829554 2016
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.050 Biomarker disease BEFREE Additionally the data presented herein suggests that splenic FoxP3- and IL-17-producing cells are involved in the chronicity of visceral leishmaniasis. 25200768 2014
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.050 AlteredExpression disease BEFREE The IL-10 production and Foxp3 expression in peripheral blood mononuclear cells from VL subjects were observed regulated significantly (p = 0.0131 and 0.0436 when compared with untreated samples) in presence of an antagonist to LFA-3. 23974052 2013
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.050 Biomarker disease LHGDN Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis. 17389235 2007
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
0.050 Biomarker disease BEFREE The data implicate IL-10-producing CD25(-)Foxp3(-) T cells in the pathogenesis of human VL. 17389235 2007