| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | PGL-1 and LID-1 antibody levels in HIV-infected and HIV-uninfected individuals in a Hansen's disease (leprosy) endemic area of Brazil. | 31757558 | 2020 | ||||
|
0.080 | Biomarker | disease | BEFREE | We evaluated the performance of two rapid serological tests (PGL1 and NDO-LID) in the discrimination of leprosy cases from healthy individuals at the Alfredo da Matta Foundation, a reference center for the disease in Manaus, Amazonas, Brazil. | 30616580 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | ELISA anti-PGL-I is the most important test in determining the increased chance of neural impairment in asymptomatic leprosy household contacts. | 29782495 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | We suggest that environmental waters containing M. leprae bacilli play an important role in disease transmission, justifying PGL-1 seropositivity in individuals living in areas where there is no reported case, and in leprosy cases individuals who report no previous contact with other case. | 28562758 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | We strongly suggest that serum IgG/IgM and salivary anti-PGL1 IgA/IgM measurements are used to follow leprosy household contacts. | 23871279 | 2013 | ||||
|
0.080 | Biomarker | disease | BEFREE | Between 2003 at 2006 there was a prospective cross-sectional clinical study with 31 contacts with patients with leprosy with positive serology against PGL-1, 05 negative controls and 01 positive control. | 20963340 | 2011 | ||||
|
0.080 | Biomarker | disease | BEFREE | An improved serological diagnostic test for leprosy could be developed by incorporating these IgG-reactive antigens to the current PGL-I based tests. | 21269435 | 2011 | ||||
|
0.080 | Biomarker | disease | BEFREE | Modified PGL-I serology incorporating new Mycobacterium leprae antigens and CMI tests based on IFN-gamma gamma production may permit the detection of leprosy PB and MB forms in endemic countries. | 19618083 | 2008 |