| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Additionally, common variants of NOD2 and LACC1 have been implicated in susceptibility to leprosy, a granulomatous infection. | 29538758 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our results showed no association between the SNP rs8057341 in NOD2 and leprosy in this population. | 30289892 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | These results clearly implicate the NOD2 pathway in the regulation of leprosy susceptibility across diverse populations. | 25367361 | 2014 | ||||
|
0.080 | Biomarker | disease | BEFREE | The addition of recombinant IL-32 restored NOD2-induced DC differentiation in patients with the progressive form of leprosy. | 22447076 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Absence of nucleotide-binding oligomerization domain-containing protein 2 variants in patients with leprosy and tuberculosis. | 22289211 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Genetic factors, such as the vitamin D receptor, the major histocompatibility complex region, chromosome 20, human toll-like receptors, the natural resistance-associated macrophage protein 1, the nucleotide-binding oligomerization domain containing 2, phosphate-regulating gene with homologies to endopeptidase on the X chromosome and the tyrosine kinase growth factor receptor-ErbB-2, contribute to both vitamin D status and leprosy. | 22170299 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We provide the example of NOD2 (Crohn's disease gene) and LTA (myocardial infarction gene) and the implication of a common genetic risk factor between these two diseases and leprosy. | 20936290 | 2011 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | These data suggest that NOD2 genetic variants are associated with susceptibility to leprosy and the development of leprosy reactive states. | 20350193 | 2010 |