Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4869
Gene Symbol: NPM1
NPM1
0.010 AlteredExpression disease BEFREE NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome. 30126426 2018
Entrez Id: 1977
Gene Symbol: EIF4E
EIF4E
0.010 Biomarker disease BEFREE This review presents aspects of eIF4E involvement in the realm of the lymphoblastic leukemia status; translational control of immunological function via eIF4E and the state-of-the-art in drugs will also be outlined. 29527921 2018
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.010 Biomarker disease BEFREE Expression and role of granulocyte macrophage colony-stimulating factor receptor (GM-CSFR) and granulocyte colony-stimulating factor receptor (G-CSFR) on Ph-positive acute B lymphoblastic leukemia. 29338593 2018
Entrez Id: 724022
Gene Symbol: MIR652
MIR652
0.010 AlteredExpression disease BEFREE Overexpression of miR-652-3p might suppress lymphoblastic leukemia cells, promoting apoptosis and increasing sensitivity to chemotherapeutic drugs. 29967774 2018
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
0.010 Biomarker disease BEFREE This paper reviews the current knowledge of the role of EZH2 in the pathogenesis of myeloid and lymphoid leukemia. 29289837 2018
Entrez Id: 23291
Gene Symbol: FBXW11
FBXW11
0.010 AlteredExpression disease BEFREE In this study, Fbxw11 expression was aberrantly upregulated in patients with lymphocytic leukemia. 29555946 2018
Entrez Id: 965
Gene Symbol: CD58
CD58
0.010 AlteredExpression disease BEFREE Role of CD81 and CD58 in minimal residual disease detection in pediatric B lymphoblastic leukemia. 29500862 2018
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
0.010 Biomarker disease BEFREE Effects of CB2 and TRPV1 receptors' stimulation in pediatric acute T-lymphoblastic leukemia. 29765535 2018
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
0.010 Biomarker disease BEFREE MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia. 29449434 2018
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
0.010 Biomarker disease BEFREE SH2B3 aberrations enriched in iAMP21 B lymphoblastic leukemia. 30005852 2018
Entrez Id: 8996
Gene Symbol: NOL3
NOL3
0.010 Biomarker disease BEFREE Listmode data from post-induction marrows were distributed from a reference lab to seven different clinical FCM labs with variable experience in B-ALL MRD. 28475275 2018
Entrez Id: 171017
Gene Symbol: ZNF384
ZNF384
0.010 GeneticVariation disease BEFREE ZNF384-rearrangements define a molecular subtype of B-ALL characterized by a pro-B-cell immunophenotype; furthermore, ZNF384-rearrangements are prevalent in mixed-phenotype acute leukemias. 29797659 2018
Entrez Id: 693210
Gene Symbol: MIR625
MIR625
0.010 AlteredExpression disease BEFREE In addition, the lymphoblastic leukemia cell lines Reh and RS4:11 were found to have lower levels of miR-625-3p than the normal B-cell line. 29967774 2018
Entrez Id: 22978
Gene Symbol: NT5C2
NT5C2
0.010 GeneticVariation disease BEFREE Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. 29990496 2018
Entrez Id: 3676
Gene Symbol: ITGA4
ITGA4
0.010 AlteredExpression disease BEFREE The study included 797 newly diagnosed CLL/small lymphocytic leukaemia patients; 279 (35%) were CD49d positive. 28386906 2017
Entrez Id: 220930
Gene Symbol: ZEB1-AS1
ZEB1-AS1
0.010 Biomarker disease BEFREE LncRNA ZEB1-AS1 contributes to STAT3 activation by associating with IL-11 in B-lymphoblastic leukemia. 28861713 2017
Entrez Id: 2022
Gene Symbol: ENG
ENG
0.010 AlteredExpression disease BEFREE We identified endoglin expression on the majority of blasts from patients with acute myeloid leukemia (AML) and acute B-lymphoblastic leukemia (B-ALL). 28351936 2017
Entrez Id: 3589
Gene Symbol: IL11
IL11
0.010 AlteredExpression disease BEFREE LncRNA ZEB1-AS1 contributes to STAT3 activation by associating with IL-11 in B-lymphoblastic leukemia. 28861713 2017
Entrez Id: 695
Gene Symbol: BTK
BTK
0.010 Biomarker disease BEFREE Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines. 27956037 2017
Entrez Id: 443
Gene Symbol: ASPA
ASPA
0.010 Biomarker disease BEFREE The aim of the present study was to investigate the growth inhibition effects of GA in combination with asparaginase (ASP), as a component of combination chemotherapy, in a lymphoblastic leukemia cell line. 29217160 2017
Entrez Id: 9453
Gene Symbol: GGPS1
GGPS1
0.010 Biomarker disease BEFREE Here, we compared the effects of a farnesyl diphosphate synthase inhibitor, zoledronate, and a geranylgeranyl diphosphate synthase (GGDPS) inhibitor, digeranyl bisphosphonate (DGBP), on lymphocytic leukemia cell proliferation and apoptosis. 28300835 2017
Entrez Id: 83853
Gene Symbol: ROPN1L
ROPN1L
0.010 Biomarker disease BEFREE The aim of the present study was to investigate the growth inhibition effects of GA in combination with asparaginase (ASP), as a component of combination chemotherapy, in a lymphoblastic leukemia cell line. 29217160 2017
Entrez Id: 29974
Gene Symbol: A1CF
A1CF
0.010 Biomarker disease BEFREE The aim of the present study was to investigate the growth inhibition effects of GA in combination with asparaginase (ASP), as a component of combination chemotherapy, in a lymphoblastic leukemia cell line. 29217160 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
0.010 Biomarker disease BEFREE CD36-positive B-lymphoblasts Predict Poor Outcome in Children With B-lymphoblastic Leukemia. 28521628 2017
Entrez Id: 7441
Gene Symbol: VPREB1
VPREB1
0.010 GeneticVariation disease BEFREE None of the B-LBL cases showed abnormal, isolated VPREB1 deletion adjacent to IGL locus, which we identified in 25% of B-ALL. 27957801 2017