Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 Biomarker disease BEFREE Loss of p19Arf in a Rag1(-/-) B-cell precursor population initiates acute B-lymphoblastic leukemia. 21622646 2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 AlteredExpression disease LHGDN These results link E2a-Pbx1 with Bmi-1 on an oncogenic pathway that is likely to play a role in the pathogenesis of human lymphoid leukemias through downregulation of the INK4A-ARF gene. 14536079 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 AlteredExpression disease BEFREE These results link E2a-Pbx1 with Bmi-1 on an oncogenic pathway that is likely to play a role in the pathogenesis of human lymphoid leukemias through downregulation of the INK4A-ARF gene. 14536079 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 Biomarker disease BEFREE The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels. 11441822 2001
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 Biomarker disease BEFREE In vitro sensitivity of T-cell lymphoblastic leukemia to UCN-01 (7-hydroxystaurosporine) is dependent on p16 protein status: a Pediatric Oncology Group study. 11118035 2000
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 Biomarker disease BEFREE These results are consistent with a role for CDKN2 and/or MTS2 in the pathogenesis of some lymphoid leukemia/lymphomas, particularly in T-ALL/lymphoblastic lymphoma. 7882348 1995
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.060 Biomarker disease BEFREE Our results suggest that loss of the CDK4I function may contribute to immortalization of human leukemia cells and play a causative role at least in development of human lymphocytic leukemias. 7919362 1994