Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.010 GeneticVariation disease BEFREE Presence of t(8;14)(q24;q32) and the c-myc gene rearrangement after transformation suggested that the chromosomal translocation followed by the activation of the c-myc proto-oncogene might be involved in the Burkitt's type transformation of the FAB-L2 leukemic clone, but not in the leukemogenesis of the initial FAB-L2 leukemia. 9402334 1997
Entrez Id: 947
Gene Symbol: CD34
CD34
0.010 GeneticVariation disease BEFREE Patients with Ph-positive ALL were older and had a significantly lower incidence of anemia and a higher incidence of peripheral leukocytosis, FAB L2 (French-American-British) morphology, common acute lymphocytic leukemia antigens (CALLA), and CD34 marker positivity. 8030658 1994
Entrez Id: 4311
Gene Symbol: MME
MME
0.010 Biomarker disease BEFREE MY+ cases were more likely to express B-associated antigens, especially CALLA, and to be FAB L2, Ph+, or to have the BCR-ABL translocation by PCR, but these differences were not statistically significant. 7807999 1994
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.300 Biomarker disease CTD_human Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. 27776115 2016
Entrez Id: 100288687
Gene Symbol: DUX4
DUX4
0.300 Biomarker disease CTD_human Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. 27776115 2016
Entrez Id: 7441
Gene Symbol: VPREB1
VPREB1
0.300 Biomarker disease CTD_human Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. 26214592 2015
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
0.300 Biomarker disease CTD_human The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias. 25730765 2015
Entrez Id: 3131
Gene Symbol: HLF
HLF
0.300 Biomarker disease CTD_human Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. 26214592 2015
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.300 Biomarker disease CTD_human Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. 26214592 2015
Entrez Id: 5079
Gene Symbol: PAX5
PAX5
0.300 Biomarker disease CTD_human Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. 26214592 2015
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
0.300 Biomarker disease CTD_human MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL. 24736461 2014
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
0.300 Biomarker disease CTD_human MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL. 24736461 2014
Entrez Id: 2356
Gene Symbol: FPGS
FPGS
0.300 Biomarker disease CTD_human Effect of folylpolyglutamate synthase A22G polymorphism on the risk and survival of patients with acute lymphoblastic leukemia. 25013492 2014
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3
0.300 Biomarker disease CTD_human The genomic landscape of hypodiploid acute lymphoblastic leukemia. 23334668 2013
Entrez Id: 7468
Gene Symbol: NSD2
NSD2
0.300 Therapeutic disease CTD_human Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. 24076604 2013
Entrez Id: 55824
Gene Symbol: PAG1
PAG1
0.300 Biomarker disease CTD_human The genomic landscape of hypodiploid acute lymphoblastic leukemia. 23334668 2013
Entrez Id: 22807
Gene Symbol: IKZF2
IKZF2
0.300 Biomarker disease CTD_human The genomic landscape of hypodiploid acute lymphoblastic leukemia. 23334668 2013
Entrez Id: 22978
Gene Symbol: NT5C2
NT5C2
0.300 Biomarker disease CTD_human Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia. 23377183 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.300 Biomarker disease CTD_human The genomic landscape of hypodiploid acute lymphoblastic leukemia. 23334668 2013
Entrez Id: 5925
Gene Symbol: RB1
RB1
0.300 Biomarker disease CTD_human The genomic landscape of hypodiploid acute lymphoblastic leukemia. 23334668 2013
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
0.300 Biomarker disease CTD_human Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia. 22674224 2012
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
0.300 Biomarker disease CTD_human Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia. 21983886 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.300 Biomarker disease CTD_human Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia. 22674224 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.300 Biomarker disease CTD_human Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia. 22674224 2012
Entrez Id: 25
Gene Symbol: ABL1
ABL1
0.300 Biomarker disease CTD_human Antileukaemia effect of rapamycin alone or in combination with daunorubicin on Ph+ acute lymphoblastic leukaemia cell line. 21898527 2012