Gene: IDH2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders. 20946881 2010
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy. 21250968 2011
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR The prognostic significance of IDH2 mutations in AML depends on the location of the mutation. 21596855 2011
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Impact of genetic features on treatment decisions in AML. 22160010 2011
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. 22397365 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. 22417203 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis. 22616558 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR The role of mutations in epigenetic regulators in myeloid malignancies. 22898539 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. 23558173 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR [Mutation of isocitrate dehydrogenase 2 (IDH2) gene in Chinese AML patients and its clinical significance]. 23815907 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Rapid detection of IDH2 (R140Q and R172K) mutations in acute myeloid leukemia. 23949315 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients. 24606448 2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016