Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 Biomarker disease BEFREE Therefore, our novel findings indicated that CUEDC2 interacted with SOCS1 to suppress SOCS1's ubiquitin-mediated degradation, JAK1-STAT3 pathway activation and leukaemogenesis of AML. 29991678 2018
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 Biomarker disease BEFREE Moreover, the JAK1/2 inhibitor ruxolitinib restored sensitivity to the BCL2 inhibitor venetoclax in AML patient cells ex vivo in different model systems and in vivo in an AML xenograft mouse model. 28619982 2017
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 GeneticVariation disease GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 GeneticVariation disease CLINVAR Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. 21436584 2011
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 GeneticVariation disease CLINVAR Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. 21680795 2011
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 GeneticVariation disease BEFREE This is the first report to demonstrate somatic JAK1 mutations in AML and suggests that JAK1 mutations may function as disease-modifying mutations in AML pathogenesis. 18160671 2008
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
0.430 CausalMutation disease CGI