Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | disease | BEFREE | Moreover, miR-150 overexpression resulted in the reduction of AML cell proliferative ability and the increase of cell apoptotic rate. | 30502345 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | Significant overexpression of hsa-miR-451a, hsa-miR-486-5p, hsa-miR-363-3p, and hsa-miR-150-5p was confirmed in AML relative to ACA and ACC. hsa-miR-184, hsa-miR-483-5p, and hsa-miR-183-5p were significantly overexpressed in ACC relative to ACA but not to AML. | 29982598 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | Our proof-of-concept animal model studies demonstrate that the FLT3L-guided miR-150 nanoparticles tend to concentrate in bone marrow, and significantly inhibit progression of FLT3-overexpressing AML in vivo, while exhibiting no obvious side effects on normal hematopoiesis. | 27280396 | 2016 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We have demonstrated that microRNA 150 (miR-150) expression is decreased in AML and that reintroducing miR-150 expression induces myeloid differentiation and inhibits proliferation of AML cells. | 26644403 | 2016 | ||||
|
0.070 | Biomarker | disease | BEFREE | Exosomes isolated from cultured AML or the plasma from mice bearing AML xenografts exhibited enrichment of miR-150 and miR-155. | 27601730 | 2016 | ||||
|
0.070 | Biomarker | disease | BEFREE | Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia. | 23391324 | 2013 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We have found that expression of miR-150 in AML cell lines, CD34+ progenitor cells from healthy individuals, and primary BC CML and AML patient samples at levels similar to miR-150 expression in normal bone marrow promotes myeloid differentiation of these cells. | 24086639 | 2013 |